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  • 1
    Janzen EG, Haire DL. Two decades of spin trapping. In: TannerDD, editor. Advances in free radical chemistry. Greenwich : JAI Press; 1990. p. 25395.
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    Kotake Y. Pharmacologic properties of phenyl N-tert-butyl nitrone. Antiox Redox Signal 1999; 1: 48199.
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    Marnett LJ. Oxyradicals and DNA damage. Carcinogenesis 2000; 21: 36170.
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    Moochhala S, Rajnakova A. Role of nitric oxide in cancer biology. Free RadicRes 1999; 31: 6719.
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    McCormick F. Signaling networks that cause cancer. Trends Cell Biol 1999; 19: 4791807.
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    Nakae D. Endogenous liver Carcinogenesis in the rat. Pathol Int 1999; 49: 102842.
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    Nakae D, Kotake Y, Kishida H, Hensley KL, Denda A, Kitayama W, Tsujiuchi T, Sang H, Stewart CA, Tabatabaie T, Floyd RA, Konishi Y. Inhibition by phenyl N-tert-butyl nitrone of early phase Carcinogenesis in the livers of rats fed a choline-deficient, L-amino acid-defined diet. Cancer Res 1998; 58: 454851.
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    Reinke LA, Moore DR, Sang H, Janzen EG, Kotake Y. Aromatic hydroxylation in PBN spin trapping by hydroxyl radicals and cytochrome P-450. Free Radic Res Biol Med 2000; 28: 34550.
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    Janzen EG, West MS, Kotake Y, DuBose CM. Biological spin trapping methodology III. Octanol-water partition coefficients of spin-trapping compounds. J Biochem. Biophys Methods 1996; 32: 18390.
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    Kishida H, Nakae D, Kobayashi Y, Kusuoka O, Kitayama W, Denda A, Fukui H, Konishi Y. Enhancement of hepatocarcinogenesis initiated with di-ethylnitrosamine or N-nitrosobis(2-hydroxypropyl)amine by a choline-deficient, L-amino acid-defined diet administered prior to the carcinogen exposure in rats. Exp Toxicol Pathol 2000; 52: 40512.
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    Campbell HA, Pilot HC, Potter VR, Laishes BA. Application of quantitative stereology to the evaluation of enzyme-altered foci in rat liver. Cancer Res 1982; 42: 46572.
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    Gold R, Schmied M, Giegerich G, Breitschopf H, Hartung HP, Toyaka KV, Lassmann H. Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques. Lab Invest 1994; 71: 21925.
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    Tsutsumi Y, Serizawa A, Kawai K. Enhanced polymer one-step staining (EPOS) for proliferating cell nuclear antigen (PCNA) and Ki-67 antigen: application to intra-operative frozen diagnosis. Pathol Int 1995; 45: 10815.
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    Nakae D, Mizumoto Y, Kobayashi E, Noguchi O, Konishi Y. Improved genomic/nuclear DNA extraction for 8-hydroxydeoxyguanosine analysis of small amounts of rat liver tissue. Cancer Lett 1995; 97: 2339.
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    Nakae D, Yamamoto K, Yoshiji H, Kinugasa T, Maruyama H, Farber JL, Konishi Y. Liposome-encapsulated superoxide dismutase prevents liver necrosis induced by acetaminophen. Am J Pathol 1990; 136: 18195.
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    Pitot HC, Campbell HA, Matonpot R, Bawa N, Rizvi TA, Xu YH, Sargent L, Dragan Y, Pyron M. Critical parameters in the quantitation of the stages of initiation, promotion, and progression in one model of hepatocarcinogenesis in the rat. Toxicol Pathol 1989; 17: 594612.
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    Nakae D, Mizumoto Y, Yoshiji H, Andoh N, Horiguchi K, Shiraiwa K, Kobayashi E, Endoh T, Shimoji N, Tamura K, Tsujiuchi T, Denda A, Konishi Y. Different roles of 8-hydroxyguanine formation and 2-thiobarbituric acid-reacting substances generation in the early phase of liver carcinogenesis induced by a choline-deficient, L-amino acid-defined diet in rats. Jpn J Cancer Res 1994; 85: 499505.
  • 18
    Kobayashi Y, Nakae D, Akai H, Kishida H, Okajima E, Kitayama W, Denda A, Tsujiuchi T, Murakami A, Koshimizu K, Ohigashi H, Konishi Y. Prevention by 1′-acetoxychavicol acetate of the induction but not growth of putative preneoplastic, glutathione S-transferase placental form-positive, focal lesions in the livers of rats fed a choline-deficient, L-amino acid-defined diet. Carcinogenesis 1998; 19: 180914.
  • 19
    Mizumoto Y, Nakae D, Yoshiji H, Andoh N, Horiguchi K, Endoh T, Kobayashi E, Tsujiuchi T, Shimoji N, Denda A, Tsujii T, Nagao M, Wakabayashi K, Konishi Y. Inhibitory effects of 2-O-octadecylascorbic acid and other vitamin C and E derivatives on the induction of enzyme-altered putative preneoplastic lesions in the livers of rats fed a choline-deficient, L-amino acid-defined diet. Carcinogenesis, 1994; 15: 2416.
  • 20
    Kawai Y, Kato Y, Nakae D, Kusuoka O, Konishi Y, Uchida K, Osawa T. Immunohistochemical detection of a substituted 1, N2-ethenodeoxyguanosine adduct by ω-6 polyunsaturated fatty acid hydroperoxide in the liver of rats fed a choline-deficient, L-amino acid-defined diet. Carcinogenesis 2002; 23: 4859.
  • 21
    Hensley K, Kotake Y, Sang H, Pye QN, Kolker WGL, Tabatabaie T, Stewart CA, Konishi Y, Nakae D, Floyd RA. Dietary choline restriction causes complex I dysfunction and increased H2O2 generation in liver mitochondria. Carcinogenesis 2000; 21: 9839.
  • 22
    Zeisel SH, Albright CD, Shin OH, Mar MH, Salganik RI, DaCosta KA. Choline deficiency selects for resistance to p53-independent apoptosis and causes tumorigenic transformation of rat hepatocytes. Carcinogenesis 1997; 18: 7318.
  • 23
    Holmes-McNary MQ, Baldwin ASJr, Zeisel SH. Opposing regulation of choline deficiency-induced apoptosis by p53 and nuclear factor KB. J Biol Chem. 2001; 276: 41197204.
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    Ohata T, Fukuda K, Murakami A, Ohigashi H, Sugimura T, Wakabayashi K. Inhibition by 1′-acetoxychavicol acetate of lipopolysaccharide- and inter-feron-γ-induced nitric oxide production through suppression of inducible nitric oxide synthase gene expression in RAW264 cells. Carcinogenesis 1998; 19: 100712.
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    Schmedtje JF Jr, Ji YS, Liu W, SuBois RN, Runge MS. Hypoxia induces cyclooxygenase-2 via the NF-kB p65 transcription factor in human vascular endothelial cells. J Biol Chem. 1997; 272: 6018.
  • 26
    Kroll B, Kunz, S, Tu N, Schwarz L. Inhibition of transforming growth factor-β1 and UV light-induced apoptosis by prostanoids in primary cultures of rat hepatocytes. Toxicol Appl Pharmacol 1998; 152: 24050.
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    McGinty A, Chang YE, Sorokin A, Bokemeyer D, Dunn MJ. Cyclooxygenase-2 expression inhibits trophic withdrawal apoptosis in nerve growth factor-differentiated PC12 cells. J Biol Chem. 2000; 275: 12095101.
  • 28
    Lax AJ, Thomas W. How bacteria could cause cancer: one step at a time. Trends Microbiol 2002; 10: 2939.
  • 29
    Denda A, Kitayama W, Murata A, Kishida H, Sasaki Y, Kusuoka O, Tsujiuchi T, Tsutsumi M, Nakae D, Takagi H, Konishi Y. Increased expression of cyclooxygenase-2 protein during rat hepatocarcinogenesis caused by a choline-deficient, L-amino acid-defined diet and chemopreventive efficacy of a specific inhibitor, nimesulide. Carcinogenesis 2002; 23: 24556.
  • 30
    Chen G, Bray TM, Janzen EG. The role of mixed function oxidase (MFO) in the metabolism of the spin trapping agent α-phenyl-N-tert-butyl-nitrone (PBN) in rats. Free Radic Res Commun 1991; 14: 916.