• 1
    Mulligan RC. The basic science of gene therapy. Science 1993; 260: 92632.
  • 2
    Ledley FD. Nonviral gene therapy: the promise of genes as pharmaceutical products. Hum Gene Ther 1995; 6: 112944.
  • 3
    Li S, Huang L. Nonviral gene therapy: promises and challenges. Gene Ther 2000; 7: 314.
  • 4
    Wheeler CJ, Felgner PL, Tsai YJ et al. A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung. Proc Natl Acad Sci USA 1996; 93: 114549.
  • 5
    Wattiaux R, Laurent N, Wattiaux-De Cornick S, Jadot M. Endosomes, lysosomes: their implication in gene transfer. Adv Drug Deliv Rev 2000; 41: 2018.
  • 6
    Farhood H, Serbina N, Huang L. The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim Biophys Acta 1995; 1235: 28995.
  • 7
    El Ouahabi A, Thirry M, Pector V, Fuks R, Ruysschaert JM, Vandenbranden M. The role of endosome destabilizing activity in the gene transfer process mediated by cationic lipids. FEBS Lett 1997; 414: 18792.
  • 8
    Murray KD, Etheridge CJ, Shah SJ et al. Enhanced cationic liposome-mediated transfection using the DNA-binding peptide mu (mu) from the adenovirus core. Gene Ther 2001; 8: 45360.
  • 9
    Saeki Y, Matsumoto N, Nakano Y, Mori M, Awai K, Kaneda Y. Development and characterization of cationic liposomes conjugated with HVJ (Sendai virus): reciprocal effect of cationic lipid for in vitro and in vivo gene transfer. Hum Gene Ther 1997; 8: 213341.
  • 10
    Bergen M, Chen R, Gonzalez R. Efficacy and safety of HLA-B7/beta-2 microglobulin plasmid DNA/lipid complex (Allovectin-7) in patients with metastatic melanoma. Expert Opin Biol Ther 2003; 3: 37784.
  • 11
    Yoshida J, Mizuno M, Fujii M et al. Human gene therapy for malignant gliomas (glioblastoma multiforme and anaplastic astrocytoma) by in vivo transduction with human interferon beta gene using cationic liposomes. Hum Gene Ther 2004; 15: 7786.
  • 12
    Siehl JM, Thiel E, Schmittel A et al. Ifosfamide/liposomal daunorubicin is a well tolerated and active first-line chemotherapy regimen in advanced soft tissue sarcoma: results of a phase II study. Cancer 2005; 104: 6117.
  • 13
    Krown SE, Northfield DW, Osoba D, Stewart JS. Use of liposomal anthracyclines in Kaposi's sarcoma. Semin Oncol 2004; 31 (6 Suppl. 13): 3652.
  • 14
    Zabner J, Fasbender AJ, Moninger T, Poellinger KA, Welsh MJ. Cellular and molecular barriers to gene transfer by a cationic lipid. J Biol Chem 1995; 270: 189979007.
  • 15
    Mesika A, Kiss V, Brumfeld V, Ghosh G, Reich Z. Enhanced intracellular mobility and nuclear accumulation of DNA plasmids associated with a karyophilic protein. Hum Gene Ther 2005; 16: 2008.
  • 16
    Subramanian A, Ranganathan P, Diamond SL. Nuclear targeting peptide scaffolds for lipofection of nondividing mammalian cells. Nat Biotechnol 1999; 17: 8737.
  • 17
    Demeneix B, Behr J, Boussif O, Zanta MA, Abdallah B, Remy J. Gene transfer with lipospermines and polyethylenimines. Adv Drug Deliv Rev 1998; 30: 8595.
  • 18
    Wolfert MA, Schacht EH, Toncheva V, Ulbrich K, Nazarova O, Seymour LW. Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers. Hum Gene Ther 1996; 7: 212333.
  • 19
    Sudimack J, Lee RJ. Targeted drug delivery via the folate receptor. Adv Drug Deliv Rev 2000; 41: 14762.
  • 20
    Qian ZM, Li H, Sun H, Ho K. Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway. Pharmacol Rev 2002; 54: 56187.
  • 21
    Hashida M, Nishikawa M, Yamashita F, Takakura Y. Cell-specific delivery of genes with glycosylated carriers. Adv Drug Deliv Rev 2001; 52: 18796.
  • 22
    Shea LD, Smiley E, Bonadio J, Mooney DJ. DNA delivery from polymer matrices for tissue engineering. Nat Biotechnol 1999; 17: 5514.
  • 23
    Kushibiki T, Matsumoto K, Nakamura T, Tabata Y. Suppression of tumor metastasis by NK4 plasmid DNA released from cationized gelatin. Gene Ther 2004; 11 (15): 120514.
  • 24
    Maeda H, Wu J, Sawa T, Matsumura Y, Hori K. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release 2000; 65: 27184.
  • 25
    Hosseinkhani H, Tabata Y. PEGylation enhances tumor targeting of plasmid DNA by an artificial cationized protein with repeated RGD sequences, Pronectin. J Control Release 2004; 97: 15771.
  • 26
    Wells D. Gene therapy progress and prospects: electroporation and other physical mthods. Gene Ther 2004; 11: 13639.
  • 27
    Liu F, Huang L. A syringe electrode device for simultaneous injection of DNA and electrotransfer. Mol Ther 2002; 3: 3238.
  • 28
    Hofmann GA, Deb SB, Nanda GS, Rabussay D. Electroporation therapy of solid tumors. Crit Rev Ther Drug Carrier Syst 1999; 16: 52369.
  • 29
    Taniyama Y, Tachibana K, Hiraoka K et al. Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle. Gene Ther 2002; 9: 37280.
  • 30
    Kim HJ, Greenleaf JF, Kinnick RR, Bronk JT, Bolander ME. Ultrasound-mediated transfection of mammalian cells. Hum Gene Ther 1996; 7: 133946.
  • 31
    Kaneda Y, Saeki Y, Morishita R. Gene therapy using HVJ-liposomes: the best of both worlds. Mol Med Today 1999; 5: 298303.
  • 32
    Okada Y. Sendai virus-induced cell fusion. In: DuzgunesN, ed. Methods in Enzymology, Vol. 221. San Diego: Academic Press, 1993; 1841.
  • 33
    Nakamura N, Hart DA, Frank CB et al. Efficient transfer of intact oligonucleotides into the nucleus of ligament scar fibroblasts by HVJ-cationic liposomes is correlated with effective antisense gene inhibition. J Biochem 2001; 129: 7559.
  • 34
    Wagner E, Plank C, Zatloukal K, Cotten M, Birnstiel ML. Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle. Proc Natl Acad Sci USA 1992; 89: 79348.
  • 35
    Zhou W-Z, Hoon DSB, Huang SKS et al. RNA melanoma vaccine: induction of anti-tumor immunity by human glycoprotein 100 mRNA immunization. Hum Gene Ther 1999; 10: 271924.
  • 36
    Kawashita Y, Ohtsuru A, Miki F et al. Eradication of hepatocellular carcinoma xenografts by radiolabelled lipiodol-inducible gene therapy. Gene Ther 2005; 12: 16339.
  • 37
    Saeki Y, Wataya-Kaneda M, Tanaka K, Kaneda Y. Sustained transgene expression in vitro and in vivo using an Epstein–Barr virus replicon vector system combined with HVJ liposomes. Gene Ther 1998; 5: 10317.
  • 38
    Otomo T, Yamamoto S, Morishita R, Kaneda Y. EBV replicon vector system enhances transgene expression in vivo: applications to gene therapy for cancer. J Gene Med 2001; 3: 34552.
  • 39
    Jahner D, Stuhlmann H, Stewart CL et al. De novo methylation and expression of retroviral genomes during mouse embryogenesis. Nature 1982; 298: 6238.
  • 40
    Henikoff S, Ahmad K. Assembly of variant histones into chromatin. Annu Rev Cell Dev Biol 2005; 21: 13353.
  • 41
    Cheng X, Collins RF, Zhang X. Structural and sequence motifs of protein (histone) methylation enzymes. Annu Rev Biophys Biomol Struct 2005; 34: 26794.
  • 42
    Yamamoto S, Yamano T, Tanaka M et al. A novel combination of suicide gene therapy and histone deacetylase inhibitor for treatment of malignant melanoma. Cancer Gene Ther 2003; 10: 17986.
  • 43
    Kaneda Y, Nakajima T, Nishikawa T et al. Hemagglutinating virus of Japan (HVJ) envelope vector as a versatile gene delivery system. Mol Ther 2002; 6: 21926.
  • 44
    Kaneda Y, Yamamoto S, Nakajima T. Development of HVJ envelope vector and its application to gene therapy. In: HuangL, HungM-C, WagnerE, eds. Non-Viral Vectors for Gene Therapy. London: Elsevier Academic Press, 2005; 30732.
  • 45
    Hirano T, Fujimoto J, Ueki T et al. Persistent gene expression in rat liver in-vivo by repetitive transfections using HVJ-liposome. Gene Ther 1998; 5: 45964.
  • 46
    Aloyz R, Xu ZY, Bello V et al. Regulation of cisplatin resistance and homologous recombinational repair by the TFIIH subunit XPD. Cancer Res 2002; 62: 545762.
  • 47
    Ito M, Yamamoto S, Nimura K, Hiraoka K, Tamai K, Kaneda Y. Rad51 siRNA delivered by HVJ envelope vector enhances the anticancer effect of cisplatin. J Gene Med 2005; 7: 104452.
  • 48
    Mima H, Tomoshige R, Kanamori T et al. Biocompatible polymer enhances the in vitro and in vivo transfection efficiency of HVJ envelope vector. J Gene Med 2005; 7: 88897.
  • 49
    Morishita N, Nakagami H, Morishita R et al. Magnetic nanoparticles with surface modification enhanced gene delivery of HVJ-E vector. Biochem Biophys Res Comm 2005; 31: 11216.