• 1
    Reppert SM, Weaver DR. Coordination of circadian timing in mammals. Nature 2002; 418: 93541.
  • 2
    Morse D, Sassone-Corsi P. Time after time: inputs to and outputs from the mammalian circadian oscillators. Trends Neurosci 2002; 25: 6327.
  • 3
    Czeisler CA, Duffy JF, Shanahan TL et al. Stability, precision, and near-24-hour period of the human circadian pacemaker. Science 1999; 284: 217781.
  • 4
    Panda S, Antoch MP, Miller BH et al. Coordinated transcription of key pathways in the mouse by the circadian clock. Cell 2002; 109: 30720.
  • 5
    Storch KF, Lipan O, Leykin I et al. Extensive and divergent circadian gene expression in liver and heart. Nature 2002; 417: 7883.
  • 6
    Delaunay F, Laudet V. Circadian clock and microarrays: mammalian genome gets rhythm. Trends Genet 2002; 18: 5957.
  • 7
    Bjarnason GA, Jordan R. Circadian variation of cell proliferation and cell cycle protein expression in man: clinical implications. Prog Cell Cycle Res 2000; 4: 193206.
  • 8
    Matsuo T, Yamaguchi S, Mitsui S, Emi A, Shimoda F, Okamura H. Control mechanism of the circadian clock for timing of cell division in vivo. Science 2003; 302: 255.
  • 9
    Smaaland R, Lote K, Sothern RB, Laerum OD. DNA synthesis and ploidy in non-Hodgkin's lymphomas demonstrate intrapatient variation depending on circadian stage of cell sampling. Cancer Res 1993; 53: 312938.
  • 10
    Duffield GE, Best JD, Meurers BH, Bittner A, Loros JJ, Dunlap JC. Circadian programs of transcriptional activation, signaling, and protein turnover revealed by microarray analysis of mammalian cells. Curr Biol 2002; 12: 5517.
  • 11
    Kornmann B, Preitner N, Rifat D, Fleuury-Olela F, Schibler U. Analysis of circadian liver gene expression by ADDER, a highly sensitive method for the display of differentially expressed mRNAs. Nucl Acids Res 2001; 29: E51.
  • 12
    Le Minh N, Damiola F, Tronche F, Schutz G, Schibler U. Glucocorticoid hormones inhibit food-induced phaseshifting of peripheral circadian oscillators. EMBO J 2001; 20: 712836.
  • 13
    Chen ST, Choo KB, Hou MF, Yeh KT, Kuo SJ, Chang JG. Deregulated expression of the PER1, PER2 and PER3 genes in breast cancers. Carcinogenesis 2005; 26: 12416.
  • 14
    Filipski E, King VM, Li X et al. Host circadian clock as a control point in tumor progression. J Natl Cancer Inst 2002; 94: 6907.
  • 15
    Dunlap JC. Molecular bases for circadian clocks. Cell 1999; 96: 27190.
  • 16
    Zheng B, Albrecht U, Kaasik K et al. Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock. Cell 2001; 105: 68394.
  • 17
    Bae K, Jin X, Maywood ES, Hastings MH, Reppert SM, Weaver DR. Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock. Neuron 2001; 30: 52536.
  • 18
    Lee CC. The circadian clock and tumor suppression by mammalian period genes. Meth Enzymol 2005; 393: 85261.
  • 19
    Fu L, Pelicano H, Liu J, Huang P, Lee C. The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo. Cell 2002; 111: 4150.
  • 20
    Wakamatsu H, Takahashi S, Moriya T et al. Additive effect of mPer1 and mPer2 antisense oligonucleotides on light-induced phase shift. Neuroreport 2001; 12: 12731.
  • 21
    Akashi M, Nishida E. Involvement of the MAP kinase cascade in resetting of the mammalian circadian clock. Genes Dev 2000; 14: 6459.
  • 22
    Akhtar RA, Reddy AB, Maywood ES et al. Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus. Curr Biol 2002; 12: 54050.
  • 23
    Bjarnason GA, Jordan RC, Sothern RB. Circadian variation in the expression of cell-cycle proteins in human oral epithelium. Am J Pathol 1999; 154: 61322.
  • 24
    Bjarnason GA, Jordan RC, Wood PA et al. Circadian expression of clock genes in human oral mucosa and skin: association with specific cell-cycle phases. Am J Pathol 2001; 158: 1793801.
  • 25
    Benchimol S. p53-dependent pathways of apoptosis. Cell Death Differ 2001; 8: 104951.
  • 26
    Yu J, Wang Z, Kinzler KW, Vogelstein B, Zhang L. PUMA mediates the apoptotic response to p53 in colorectal cancer cells. Proc Natl Acad Sci USA 2003; 100: 19316.
  • 27
    Ghobrial IM, Witzig TE, Adjei AA. Targeting apoptosis pathways in cancer therapy. CA Cancer J Clin 2005; 55: 17894.
  • 28
    Ho J, Ma W, Mao D, Benchimol S. p53-dependent transcriptional repression of c-myc is required for G1 cell cycle arrest. Mol Cellular Biol 2005; 25 (17): 742331.
  • 29
    Cory S, Adams JM. The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2002; 2: 64756.
  • 30
    Liou AKF, Clark RS, Henshall DC, Yin XM, Chen J. To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress activated signaling pathways and apoptotic pathways. Prog Neurobiol 2003; 69: 10342.