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Fig. S1. The effects of celecoxib and PC-407 (4-[5-naphthyl-3-(trifluoromethyl)-1H-pyrazol-1-yl] benzenesulfonamide) on the mRNA level of cyclooxygenase-2 (COX-2), and the protein level of COX-2, COX-1, Bcl-2, Bax, caspase-3, -8, -9, phospho-GSK-3β, β-catenin, and phospho-β-catenin in colorectal cancer (CRC) cells or azoxymethane/dextran sodium sulfate (AOM/DSS)-treated ICR mice. "Quantity one" of Bio-Rad was used to analyze the results of RT-PCR and Western blotting. SPSS 11.0 (SPSS, Chicago, IL, USA) was employed to deal with the data. *P < 120.05 and **P < 0.01 vs control. (a) Results of RT-PCR; (b) results of Western blotting.

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