• 1
    Raut CP, Grau AM, Staerkel GA et al. Diagnostic accuracy of endoscopic ultrasound-guided fine-needle aspiration in patients with presumed pancreatic cancer. J Gastrointest Surg 2003; 7: 11826.
  • 2
    Agarwal B, Abu-Hamda E, Molke KL, Correa AM, Ho L. Endoscopic ultrasound-guided fine needle aspiration and multidetector spiral CT in the diagnosis of pancreatic cancer. Am J Gastroenterol 2004; 99: 84450.
    Direct Link:
  • 3
    Eloubeidi MA, Tamhane A. EUS-guided FNA of solid pancreatic masses: a learning curve with 300 consecutive procedures. Gastrointest Endosc 2005; 61: 7008.
  • 4
    Pugliese V, Pujic N, Saccomanno S et al. Pancreatic intraductal sampling during ERCP in patients with chronic pancreatitis and pancreatic cancer: cytologic studies and k-ras-2 codon 12 molecular analysis in 47 cases. Gastrointest Endosc 2001; 54: 5959.
  • 5
    Vandervoort J, Soetikno RM, Montes H et al. Accuracy and complication rate of brush cytology from bile duct versus pancreatic duct. Gastrointest Endosc 1999; 49: 3227.
  • 6
    McGuire DE, Venu RP, Brown RD et al. Brush cytology for pancreatic carcinoma: an analysis of factors influencing results. Gastrointest Endosc 1996; 44: 3004.
  • 7
    Uchida N, Kamada H, Tsutsui K et al. Utility of pancreatic duct brushing for diagnosis of pancreatic carcinoma. J Gastroenterol 2007; 42: 65762.
  • 8
    Takahashi Y, Le Douarin N. cDNA cloning of a quail homeobox gene and its expression in neural crest-derived mesenchyme and lateral plate mesoderm. Proc Natl Acad Sci USA 1990; 87: 74826.
  • 9
    Davidson DR, Crawley A, Hill RE, Tickle C. Position-dependent expression of two related homeobox genes in developing vertebrate limbs. Nature 1991; 352: 42931.
  • 10
    Jowett AK, Vainio S, Ferguson MW, Sharpe PT, Thesleff I. Epithelial-mesenchymal interactions are required for msx 1 and msx 2 gene expression in the developing murine molar tooth. Development 1993; 117: 46170.
  • 11
    Phippard DJ, Weber-Hall SJ, Sharpe PT et al. Regulation of Msx-1, Msx-2, Bmp-2 and Bmp-4 during foetal and postnatal mammary gland development. Development 1996; 122: 272937.
  • 12
    Satoh K, Ginsburg E, Vonderhaar BK. Msx-1 and Msx-2 in mammary gland development. J Mammary Gland Biol Neoplasia 2004; 9: 195205.
  • 13
    Satoh K, Hovey RC, Malewski T et al. Progesterone enhances branching morphogenesis in the mouse mammary gland by increased expression of Msx2. Oncogene 2007; 26: 752634.
  • 14
    Suzuki M, Tanaka M, Iwase T et al. Over-expression of HOX-8, the human homologue of the mouse Hox-8 homeobox gene, in human tumors. Biochem Biophys Res Commun 1993; 194: 18793.
  • 15
    Apte MV, Haber PS, Applegate TL et al. Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture. Gut 1998; 43: 12833.
  • 16
    Satoh K, Hamada S, Kimura K et al. Up-regulation of MSX2 enhances the malignant phenotype and is associated with twist 1 expression in human pancreatic cancer cells. Am J Pathol 2008; 172: 92639.
  • 17
    Satoh K, Hamada S, Kanno A et al. Expression of MSX2 predicts malignancy of branch duct intraductal papillary mucinous neoplasm of the pancreas. J Gastroenterol 2010; 45: 76370.
  • 18
    Goodale RL, Gajl-Peczalska K, Dressel T, Samuelson J. Cytologic studies for the diagnosis of pancreatic cancer. Cancer 1981; 47: 16525.
  • 19
    Hruban RH, Goggins M, Parsons J, Kern SE. Progression model for pancreatic cancer. Clin Cancer Res 2000; 6: 296972.
  • 20
    Satoh K, Sawai T, Shimosegawa T et al. The point mutation of c-Ki-ras at codon 12 in carcinoma of the pancreatic head region and in intraductal mucin-hypersecreting neoplasm of the pancreas. Int J Pancreatol 1993; 14: 13543.
  • 21
    Yanagisawa A, Ohtake K, Ohashi K et al. Frequent c-Ki-ras oncogene activation in mucous cell hyperplasias of pancreas suffering from chronic inflammation. Cancer Res 1993; 53: 9536.
  • 22
    Parsi MA, Li A, Li CP, Goggins M. DNA methylation alterations in endoscopic retrograde cholangiopancreatography brush samples of patients with suspected pancreaticobiliary disease. Clin Gastroenterol Hepatol 2008; 6: 12708.
  • 23
    Ohuchida K, Mizumoto K, Ogura Y et al. Quantitative assessment of telomerase activity and human telomerase reverse transcriptase messenger RNA levels in pancreatic juice samples for the diagnosis of pancreatic cancer. Clin Cancer Res 2005; 11: 228592.
  • 24
    Wang Y, Gao J, Li Z et al. Diagnostic value of mucins (MUC1, MUC2 and MUC5AC) expression profile in endoscopic ultrasound-guided fine-needle aspiration specimens of the pancreas. Int J Cancer 2007; 121: 271622.
  • 25
    Takahashi C, Akiyama N, Matsuzaki T et al. Characterization of a human MSX-2 cDNA and its fragment isolated as a transformation suppressor gene against v-Ki-ras oncogene. Oncogene 1996; 12: 213746.
  • 26
    Hamada S, Satoh K, Hirota M et al. Bone morphogenetic protein 4 induces epithelial-mesenchymal transition through MSX2 induction on pancreatic cancer cell line. J Cell Physiol 2007; 213: 76874.
  • 27
    Shimosegawa T, Kume K, Satoh K. Chronic pancreatitis and pancreatic cancer: prediction and mechanism. Clin Gastroenterol Hepatol 2009; 7: S238.