Increased c-Myc activity and DNA damage in hematopoietic progenitors precede myeloproliferative disease in Spa-1-deficiency
Version of Record online: 2 FEB 2011
© 2011 Japanese Cancer Association
Volume 102, Issue 4, pages 784–791, April 2011
How to Cite
Tanaka, H., Tamura, A., Sekai, M., Hamazaki, Y. and Minato, N. (2011), Increased c-Myc activity and DNA damage in hematopoietic progenitors precede myeloproliferative disease in Spa-1-deficiency. Cancer Science, 102: 784–791. doi: 10.1111/j.1349-7006.2011.01850.x
- Issue online: 18 MAR 2011
- Version of Record online: 2 FEB 2011
- Accepted manuscript online: 4 JAN 2011 11:58AM EST
- (Received October 29, 2010/Revised December 21, 2010/Accepted December 23, 2010)/Accepted manuscript online January 4, 2011)
Fig. S1. Activation of p38MAPK, but not ERK, in Spa-1−/− hematopoietic progenitor cells (HPCs).
Fig. S2. Myeloproliferative disorder (MPD) in Spa-1−/− mice is transferable to Rag2−/− mice and progresses to blast crisis (BC) during the passage in vivo.
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