These authors contributed equally to this work.
Downregulation of GRIM-19 promotes growth and migration of human glioma cells
Article first published online: 22 SEP 2011
© 2011 Japanese Cancer Association
Volume 102, Issue 11, pages 1991–1999, November 2011
How to Cite
Zhang, Y., Hao, H., Zhao, S., Liu, Q., Yuan, Q., Ni, S., Wang, F., Liu, S., Wang, L. and Hao, A. (2011), Downregulation of GRIM-19 promotes growth and migration of human glioma cells. Cancer Science, 102: 1991–1999. doi: 10.1111/j.1349-7006.2011.02059.x
- Issue published online: 23 OCT 2011
- Article first published online: 22 SEP 2011
- Accepted manuscript online: 9 AUG 2011 12:41PM EST
- (Received February 15, 2011/Revised June 21, 2011; July 22, 2011/Accepted August 1, 2011/Accepted manuscript online August 9, 2011/Article first published online September 22, 2011)
Fig. S1. GRIM-19 protein expression in U251MG and U87MG malignant glioma cells transfected with various vectors.
Fig. S2. Effect of GRIM-19 on STAT3 nuclear translocation in malignant glioma cells using double immunofluorescence staining.
Fig. S3. Expression of STAT3-dependent genes in U251MG malignant glioma cells with different treatments using RT-PCR.
Fig. S4. Expression of STAT3 target genes in U251MG malignant glioma cells with different treatments. Induction of endogenous GRIM-19 reduced interleukin (IL)-6-stimulated STAT3 nuclear translocation
Fig. S5. Expression of two STAT3-independent genes in U251MG malignant glioma cells following different treatments.
Table S1. Primers used for RT-PCR analysis.
Table S2. GRIM-19 protein expression in glioma samples.
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