Identification of a claudin-4 and E-cadherin score to predict prognosis in breast cancer
Article first published online: 12 OCT 2011
© 2011 Japanese Cancer Association
Volume 102, Issue 12, pages 2248–2254, December 2011
How to Cite
Szasz, A. M., Nemeth, Z., Gyorffy, B., Micsinai, M., Krenacs, T., Baranyai, Z., Harsanyi, L., Kiss, A., Schaff, Z., Tokes, A.-M. and Kulka, J. (2011), Identification of a claudin-4 and E-cadherin score to predict prognosis in breast cancer. Cancer Science, 102: 2248–2254. doi: 10.1111/j.1349-7006.2011.02085.x
- Issue published online: 20 NOV 2011
- Article first published online: 12 OCT 2011
- Accepted manuscript online: 29 AUG 2011 11:35AM EST
- (Received June 15, 2011/Revised August 8, 2011; August 16, 2011/Accepted August 22, 2011/Accepted manuscript online August 29, 2011)
Fig. S1. Recurrence-free survival curves according to histology, grade, and intrinsic subtype are shown in the training and validation cohort of patient samples.
Fig. S2. Immunostaining for E-cadherin and claudin-4.
Fig. S3. Kaplan–Meier graphs showing the simplified tight junction signature’s performance in the prediction of relapse-free, overall, and distant metastasis-free survival.
Fig. S4. Hierarchical clustering showing the contribution of the investigated proteins to the delineation of breast cancer cohorts.
Fig. S5. Kaplan–Meier graphs of the groups defined by the expression (below and above median) of evaluated claudin and E-cadherin proteins, individually.
Fig. S6. Performance of the claudin-4 and E-cadherin score on Kaplan–Meier graphs in the breast cancer groups with different oncological treatment.
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