Fig. S1. Positive control of IMP3 immunohistochemical staining in gastric adenocarcinoma. Brown color denotes positive staining. Original magnification, ×200.

Fig. S2. (A) SK-N-SH neuroblastoma cells showing neurite extension after treatment with all-trans retinoic acid (RA) for 3 days. (B) IMP3 protein expression levels in SK-N-SH cells, a MYCN non-amplified cell line, decreased after cell differentiation induced by RA. (C) IMP3 protein expression levels in SK-N-SH cells decreased after IMP3 knockdown by shIMP3-1 or shIMP3-2, resulting in inhibited cell migration. *< 0.05.

Fig. S3. Apoptotic cell death increased in SK-N-DZ neuroblastoma cells after IMP3 knockdown by shIMP3-1 or shIMP3-2. *< 0.05.

Table S1. Differentially expressed genes in neuroblastoma tumor tissues evaluated by oligonucleotide microarray according to patient outcome.

Data S1. Supplementary materials and methods.

CAS_2100_sm_dataS1andtS1.doc817KSupporting info item
CAS_2100_sm_fS1.jpg3859KSupporting info item
CAS_2100_sm_fS2.jpg2430KSupporting info item
CAS_2100_sm_fS3.jpg1433KSupporting info item

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