HIV prevalence among injection drug users in rural Guangxi China

  1. Wei Liu1,
  2. Jie Chen1,
  3. Michelle Rodolph2,
  4. Geetha Beauchamp3,
  5. Benoît Mâsse3,
  6. Shaoping Wang4,
  7. Rongjian Li1,
  8. Yuhua Ruan5,
  9. Feng Zhou5,
  10. Man-kit Leung2,
  11. Shenghan Lai2,
  12. Yiming Shao5,
  13. J. Brooks Jackson2,*

Article first published online: 8 AUG 2006

DOI: 10.1111/j.1360-0443.2006.01557.x

Issue

Addiction

Addiction

Volume 101, Issue 10, pages 1493–1498, October 2006

Additional Information

How to Cite

Liu, W., Chen, J., Rodolph, M., Beauchamp, G., Mâsse, B., Wang, S., Li, R., Ruan, Y., Zhou, F., Leung, M.-k., Lai, S., Shao, Y. and Jackson, J. B. (2006), HIV prevalence among injection drug users in rural Guangxi China. Addiction, 101: 1493–1498. doi: 10.1111/j.1360-0443.2006.01557.x

Author Information

  1. 1

    Guangxi Centers for Disease Control and Prevention, Nanning, China,

  2. 2

    Johns Hopkins University School of Medicine, Baltimore, MD, USA,

  3. 3

    Statistical Center for HIV/AIDS Research and Prevention, Seattle WA, USA,

  4. 4

    Heng County Health and Anti-Epidemic Station, Hengzhou, China and

  5. 5

    State Key Laboratory for Infectious Disease Prevention and Control, and National Center for AIDS/STD Control and Prevention, China Center for Disease Control and Prevention, Beijing, China

*J. Brooks Jackson, Carnegie 415, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD, 21287, USA. E-mail: bjackso@jhmi.edu

Publication History

  1. Issue published online: 1 SEP 2006
  2. Article first published online: 8 AUG 2006
  3. Submitted 28 March 2005; initial review completed 24 May 2005; final version accepted 7 March 2006

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Keywords:

  • AIDS;
  • China;
  • Guangxi;
  • HIV seroprevalence;
  • IDU

ABSTRACT

Aims  To determine the HIV-1 seroprevalence, risk behaviors and demographic characteristics associated with HIV-1 infection among injection drug users (IDU) in rural Guangxi, China.

Design and setting  Between July and November 2002, 702 IDU were screened for HIV-1 antibody through community outreach in rural Guangxi, China for enrollment in an HIV sero-incidence study.

Participants  A total of 702 active high-risk IDU were screened. High-risk injection was defined as anyone who reported injecting drugs at least three times per week in the last month or injected drugs with shared equipment on at least three occasions in the last 3 months. 

Measurements  HIV-1 antibody testing with confirmation by Western blot was performed on all subjects. Demographic and risk assessment survey data were collected at screening from everyone whose baseline HIV antibody status was known. 

Findings  HIV-1 antibody prevalence among 702 IDU at baseline was 25% with a median age of 26.7 years (18.2–43.2). Based on a multivariate logistic regression model using risk factors identified in univariate analyses, the following risk factors were associated significantly with an increase in risk for HIV seropositivity: age > 26 years (OR 1.50; 95% CI 1.04, 2.17), sharing of rinse water (OR = 1.24; 95% CI 1.09, 1.40), not having sex in the last 6 months (OR = 1.62; 95% CI 1.08, 2.43).

Conclusions  HIV infection among IDU in Guangxi, one of China’s major HIV epidemic regions, is high and the infection occurs predominantly among older IDU males who share rinse water.

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