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  • 1
    Burton R. The Anatomy of Melancholy. London: J. M. Dent and Sons Ltd; 1972.
  • 2
    Plutarch. The Training of Children. Available from: http://www.fordham.edu/Halsall/ancient/plutarch-education.html (accessed 20 November 2007).
  • 3
    Cotton N. S. The familial incidence of alcoholism: a review. J Stud Alcohol 1979; 40: 89116.
  • 4
    Guze S. B., Cloninger C. R., Martin R., Clayton P. J. Alcoholism as a medical disorder. Compr Psychiatry 1986; 27: 50110.
  • 5
    Dawson D. A., Harford T. C., Grant B. F. Family history as a predictor of alcohol dependence. Alcohol Clin Exp Res 1992; 16: 5725.
  • 6
    Cardno A., McGuffin P. Quantitiative genetics. In: McGuffinP., OwenM., GottesmanI. I., editors. Psychiatric Genetics and Genomics. Oxford: Oxford University Press; 2002, p. 3153.
  • 7
    Goodwin D. W., Schulsinger F., Moller N., Hermansen L., Winokur G., Guze S. B. Drinking problems in adopted and nonadopted sons of alcoholics. Arch Gen Psychiatry 1974; 31: 1649.
  • 8
    Goodwin D. W., Schulsinger F., Knop J., Mednick S., Guze S. B. Psychopathology in adopted and nonadopted daughters of alcoholics. Arch Gen Psychiatry 1977; 34: 10059.
  • 9
    Ball D., Collier D. Substance misuse. In: McGuffinP., OwenM. J., GottesmanI. I., editors. Psychiatric Genetics and Genomics. Oxford: Oxford University Press; 2002, p. 267302.
  • 10
    Ball D., Pembrey M., Stevens D. N. Genomics. In: NuttD., RobbinsT. W., StimsonG. V., InceM., JacksonA., editors. Drugs and the Future. London: Academic Press; 2007, p. 89131.
  • 11
    Li M. D. The genetics of smoking related behavior: a brief review. Am J Med Sci 2003; 326: 16873.
  • 12
    Tsuang M. T., Lyons M. J., Eisen S. A., Goldberg J., True W., Lin N. et al. Genetic influences on DSM-III-R drug abuse and dependence: a study of 3372 twin pairs. Am J Med Genet 1996; 67: 4737.
  • 13
    Tsuang M. T., Bar J. L., Harley R. M., Lyons M. J. The Harvard Twin Study of Substance Abuse: what we have learned. Harv Rev Psychiatry 2001; 9: 26779.
  • 14
    Karkowski L. M., Prescott C. A., Kendler K. S. Multivariate assessment of factors influencing illicit substance use in twins from female–female pairs. Am J Med Genet 2000; 96: 66570.
  • 15
    Kendler K. S., Karkowski L. M., Neale M. C., Prescott C. A. Illicit psychoactive substance use, heavy use, abuse, and dependence in a US population-based sample of male twins. Arch Gen Psychiatry 2000; 57: 2619.
  • 16
    Sham P., McGuffin P. Linkage and association. In: McGuffinP., OwenM., GottesmanI. I., editors. Psychiatric Genetics and Genomics. Oxford: Oxford University Press; 2002, p. 5573.
  • 17
    Gusella J. F., MacDonald M. E. Huntington's disease: seeing the pathogenic process through a genetic lens. Trends Biochem Sci 2006; 31: 53340.
  • 18
    Reich T., Edenberg H. J., Goate A., Williams J. T., Rice J. P., Van Eerdewegh P. et al. Genome-wide search for genes affecting the risk for alcohol dependence. Am J Med Genet 1998; 81: 20715.
  • 19
    Hesselbrock V., Foroud T., Edenberg H. J., Nurnberger J. Jr, Reich T., Rice J. Genetics and alcoholism: the COGA Project. In: AgarwalD. P., SeitzH. K., editors. Alcohol in Health and Disease. New York: Marcel Dekker Inc.; 2001, p. 10324.
  • 20
    Long J. C., Knowler W. C., Hanson R. L., Robin R. W., Urbanek M., Moore E. et al. Evidence for genetic linkage to alcohol dependence on chromosomes 4 and 11 from an autosome-wide scan in an American Indian population. Am J Med Genet 1998; 81: 21621.
  • 21
    Hill S. Y., Shen S., Zezza N., Hoffman E. K., Perlin M., Allan W. A genome wide search for alcoholism susceptibility genes. Am J Med Genet B Neuropsychiatr Genet 2004; 128: 10213.
  • 22
    Kuo P. H., Neale M. C., Riley B. P., Webb B. T., Sullivan P. F., Vittum J. et al. Identification of susceptibility loci for alcohol-related traits in the Irish Affected Sib Pair Study of Alcohol Dependence. Alcohol Clin Exp Res 2006; 30: 180716.
  • 23
    Prescott C. A., Sullivan P. F., Kuo P. H., Webb B. T., Vittum J., Patterson D. G. et al. Genomewide linkage study in the Irish Affected Sib Pair Study of Alcohol Dependence: evidence for a susceptibility region for symptoms of alcohol dependence on chromosome 4. Mol Psychiatry 2006; 11: 60311.
  • 24
    Prescott C. A., Sullivan P. F., Myers J. M., Patterson D. G., Devitt M., Halberstadt L. J. et al. The Irish Affected Sib Pair Study of Alcohol Dependence: study methodology and validation of diagnosis by interview and family history. Alcohol Clin Exp Res 2005; 29: 41729.
  • 25
    Ehlers C. L., Gilder D. A., Wall T. L., Phillips E., Feiler H., Wilhelmsen K. C. Genomic screen for loci associated with alcohol dependence in Mission Indians. Am J Med Genet B Neuropsychiatr Genet 2004; 129: 11015.
  • 26
    Wolff P. H. Ethnic differences in alcohol sensitivity. Science 1972; 175: 44950.
  • 27
    Higuchi S., Matsushita S., Masaki T., Yokoyama A., Kimura M., Suzuki G. et al. Influence of genetic variations of ethanol-metabolizing enzymes on phenotypes of alcohol-related disorders. Ann NY Acad Sci 2004; 1025: 47280.
  • 28
    Yin S. J., Agarwal D. P. Functional polymorphism of ADH and ALDH. In: AgarwalD. P., SeitzH. K., editors. Alcohol in Health and Disease. New York: Marcel Dekker; 2001, p. 126.
  • 29
    Petersen E. N. The pharmacology and toxicology of disulfiram and its metabolites. Acta Psychiatr Scand Suppl 1992; 369: 713.
  • 30
    Chick J. Safety issues concerning the use of disulfiram in treating alcohol dependence. Drug Saf 1999; 20: 42735.
  • 31
    Harada S., Agarwal D. P., Goedde H. W. Mechanism of alcohol sensitivity and disulfiram–ethanol reaction. Subst Alcohol Actions Misuse 1982; 3: 10715.
  • 32
    Higuchi S., Matsushita S., Murayama M., Takagi S., Hayashida M. Alcohol and aldehyde dehydrogenase polymorphisms and the risk for alcoholism. Am J Psychiatry 1995; 152: 121921.
  • 33
    Agarwal D. P., Goedde H. W. Genetic variation in alcohol metabolizing enzymes: implications in alcohol use and abuse. Prog Clin Biol Res 1987; 241: 12139.
  • 34
    Chen Y. C., Lu R. B., Peng G. S., Wang M. F., Wang H. K., Ko H. C. et al. Alcohol metabolism and cardiovascular response in an alcoholic patient homozygous for the ALDH2*2 variant gene allele. Alcohol Clin Exp Res 1999; 23: 185360.
  • 35
    Higuchi S., Matsushita S., Kashima H. New findings on the genetic influences on alcohol use and dependence. Curr Opin Psychiatry 2006; 19: 25365.
  • 36
    Dick D. M., Foroud T. Candidate genes for alcohol dependence: a review of genetic evidence from human studies. Alcohol Clin Exp Res 2003; 27: 86879.
  • 37
    Dick D. M., Bierut L. J. The genetics of alcohol dependence. Curr Psychiatry Rep 2006; 8: 1517.
  • 38
    Saxon A. J., Oreskovich M. R., Brkanac Z. Genetic determinants of addiction to opioids and cocaine. Harv Rev Psychiatry 2005; 13: 21832.
  • 39
    Kreek M. J., Bart G., Lilly C., LaForge K. S., Nielsen D. A. Pharmacogenetics and human molecular genetics of opiate and cocaine addictions and their treatments. Pharmacol Rev 2005; 57: 126.
  • 40
    Arinami T., Ishiguro H., Onaivi E. S. Polymorphisms in genes involved in neurotransmission in relation to smoking. Eur J Pharmacol 2000; 410: 21526.
  • 41
    Al K. N., Tyndale R. F. Genetic influences on smoking: a brief review. Ther Drug Monit 2005; 27: 7049.
  • 42
    Munafo M., Clark T., Johnstone E., Murphy M., Walton R. The genetic basis for smoking behavior: a systematic review and meta-analysis. Nicotine Tob Res 2004; 6: 58397.
  • 43
    Li M. D. The genetics of nicotine dependence. Curr Psychiatry Rep 2006; 8: 15864.
  • 44
    Saccone S. F., Hinrichs A. L., Saccone N. L., Chase G. A., Konvicka K., Madden P. A. et al. Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Hum Mol Genet 2007; 16: 3649.
  • 45
    Buckland P. R. Genetic association studies of alcoholism—problems with the candidate gene approach. Alcohol Alcohol 2001; 36: 99103.
  • 46
    Gottesman I. I., Gould T. D. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003; 160: 63645.
  • 47
    Dick D. M., Jones K., Saccone N., Hinrichs A., Wang J. C., Goate A. et al. Endophenotypes successfully lead to gene identification: results from the collaborative study on the genetics of alcoholism. Behav Genet 2006; 36: 11226.
  • 48
    Edenberg H. J., Dick D. M., Xuei X., Tian H., Almasy L., Bauer L. O. et al. Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. Am J Hum Genet 2004; 74: 70514.
  • 49
    Lusher J., Chandler C., Ball D. A contemporary investigation into vulnerability factors of alcoholism: a distinct substance of abuse. In: YoshidaR., editor. Trends in Alcohol Abuse and Alcoholism Research. New York: Nova Science Publishers, Inc.; 2006, p. 21979.
  • 50
    Lusher J. M., Chandler C., Ball D. Dopamine D4 receptor gene (DRD4) is associated with novelty seeking (NS) and substance abuse: the saga continues. Mol Psychiatry 2001; 6: 4979.
  • 51
    Schena M., Heller R. A., Theriault T. P., Konrad K., Lachenmeier E., Davis R. W. Microarrays: biotechnology's discovery platform for functional genomics. Trends Biotechnol 1998; 16: 3016.
  • 52
    Schmith V. D., Campbell D. A., Sehgal S., Anderson W. H., Burns D. K., Middleton L. T. et al. Pharmacogenetics and disease genetics of complex diseases. Cell Mol Life Sci 2003; 60: 163646.
  • 53
    Uhl G. R., Liu Q. R., Drgon T., Johnson C., Walther D., Rose J. E. Molecular genetics of nicotine dependence and abstinence: whole genome association using 520 000 SNPs. BMC Genet 2007; 8: 10.
  • 54
    Bierut L. J., Madden P. A., Breslau N., Johnson E. O., Hatsukami D., Pomerleau O. F. et al. Novel genes identified in a high-density genome wide association study for nicotine dependence. Hum Mol Genet 2007; 16: 2435.
  • 55
    Fisher P. J., Turic D., Williams N. M., McGuffin P., Asherson P., Ball D. et al. DNA pooling identifies QTLs on chromosome 4 for general cognitive ability in children. Hum Mol Genet 1999; 8: 91522.
  • 56
    Caspi A., Sugden K., Moffitt T. E., Taylor A., Craig I. W., Harrington H. et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003; 301: 3869.
  • 57
    Caspi A., McClay J., Moffitt T. E., Mill J., Martin J., Craig I. W. et al. Role of genotype in the cycle of violence in maltreated children. Science 2002; 297: 8514.
  • 58
    Kaufman J., Yang B. Z., Douglas-Palumberi H., Crouse-Artus M., Lipschitz D., Krystal J. H. et al. Genetic and environmental predictors of early alcohol use. Biol Psychiatry 2007; 61: 122834.
  • 59
    Dick D. M., Agrawal A., Schuckit M. A., Bierut L., Hinrichs A., Fox L. et al. Marital status, alcohol dependence, and GABRA2: evidence for gene–environment correlation and interaction. J Stud Alcohol 2006; 67: 18594.
  • 60
    Lusher J., Chandler C., Ball D. Alcohol dependence and the alcohol Stroop paradigm: evidence and issues. Drug Alcohol Depend 2004; 75: 22531.
  • 61
    Uhl G. R. Molecular genetics of substance abuse vulnerability: remarkable recent convergence of genome scan results. Ann NY Acad Sci 2004; 1025: 113.
  • 62
    Uhl G. R., Drgon T., Johnson C., Fatusin O. O., Liu Q. R., Contoreggi C. et al. ‘Higher order’ addiction molecular genetics: convergent data from genome-wide association in humans and mice. Biochem Pharmacol 2007; Epub before print 25 July 2007. Available from: http://dx.doi.org/10.1016/j.bcp.2007.06.042 (accessed 20 November 2007).
  • 63
    Müller-Hill B. Murderous Science. Elimination by Scientific Selection of Jews, Gypsies, and Others in Germany, 1933–45. Plainview, NY: Cold Spring Harbor Laboratory Press; 1998.
  • 64
    Gattaca [motion picture] Dir: Andrew Niccol. USA: Columbia Tristar/Jersey; 1997.
  • 65
    Bittles A. H., Neel J. V. The costs of human inbreeding and their implications for variations at the DNA level. Nat Genet 1994; 8: 11721.