Data in the following manuscript were derived from three clinical trials. Two of these trials are registered with the National Institutes of Health (NIH), and can be accessed at http://clinicaltrials.gov; ‘Maintaining Abstinence in Chronic Cigarette Smokers’ (identifier: NCT00087880) and ‘Maintaining Nonsmoking: Older Smokers’ (identifier: NCT00086385). Per NIH regulations, the third trial was not entered into a publicly accessible database because it was funded by a multiple project center grant and hence exempt from the registration requirement.
Evaluating the validities of different DSM-IV-based conceptual constructs of tobacco dependence*
Article first published online: 28 JUN 2008
© 2008 The Authors. Journal compilation © 2008 Society for the Study of Addiction
Volume 103, Issue 7, pages 1215–1223, July 2008
How to Cite
Hendricks, P. S., Prochaska, J. J., Humfleet, G. L. and Hall, S. M. (2008), Evaluating the validities of different DSM-IV-based conceptual constructs of tobacco dependence. Addiction, 103: 1215–1223. doi: 10.1111/j.1360-0443.2008.02232.x
- Issue published online: 28 JUN 2008
- Article first published online: 28 JUN 2008
- Submitted 2 October 2007; initial review completed 2 January 2008; final version accepted 26 February 2008
- tobacco dependence
Aim To compare the concurrent and predictive validities of two subsets of DSM-IV criteria for nicotine dependence (tolerance and withdrawal; withdrawal; difficulty controlling use; and use despite harm) to the concurrent and predictive validity of the full DSM-IV criteria.
Design Analysis of baseline and outcome data from three randomized clinical trials of cigarette smoking treatment.
Setting San Francisco, California.
Participants Two samples of cigarette smokers (n = 810 and 322), differing with regard to baseline characteristics and treatment received, derived from three randomized clinical trials.
Measurements DSM-IV nicotine dependence criteria were measured at baseline with a computerized version of the Diagnostic Interview Schedule for DSM-IV (DIS-IV). Additional baseline measures included the Fagerström Test of Nicotine Dependence (FTND), number of cigarettes smoked per day, breath carbon monoxide (CO) level, the Minnesota Nicotine Withdrawal Scale (MNWS), the Michigan Nicotine Reinforcement Questionnaire (M-NRQ) and the Profile of Mood States (POMS). Seven-day point-prevalence abstinence was assessed at week 12.
Findings Full DSM-IV criteria displayed greater concurrent validity than either of the two subsets of criteria. However, DSM-IV symptoms accounted for only a nominal amount of the variance in baseline smoking-related characteristics and were unrelated to smoking abstinence at week 12. Cigarettes smoked per day was the only significant predictor of abstinence at week 12.
Conclusions Although the findings do not provide a compelling alternative to the full set of DSM-IV nicotine dependence criteria, its poor psychometric properties and low predictive power limit its clinical and research utility.