• 1
    Audrain-McGovern J., Nigg J. T., Perkins K. A. Endophenotypes for nicotine-dependence risk at or before initial nicotine exposure. National Cancer Institute. Phenotypes and Endophenotypes: Foundations for Genetic Studies of Nicotine Use and Dependence. Tobacco Control Monograph no. 20. NIH Publication no. 09-6366; August. Bethesda, MD: US Department of Health and Human Services, National Institutes of Health, National Cancer Institute; 2009, p. 339402.
  • 2
    Alexander C. S., Allen P., Crawford M. A., McCormick L. K. Taking a first puff: cigarette smoking experiences among ethnically diverse adolescents. Ethn Health 1999; 4: 24557.
  • 3
    Pomerleau O. F., Pomerleau C. S., Namenek R. J. Early experiences with tobacco among women smokers, ex-smokers, and never-smokers. Addiction 1998; 93: 5959.
  • 4
    DiFranza J. R., Savageau J. A., Fletcher K., Ockene J. K., Rigotti N. A., McNeill A. D. et al. Recollections and repercussions of the first inhaled cigarette. Addict Behav 2004; 29: 26172.
  • 5
    Eissenberg T., Balster R. L. Initial tobacco use episodes in children and adolescents: current knowledge, future directions. Drug Alcohol Depend 2000; 59: S4160.
  • 6
    Pomerleau O. F. Individual differences in sensitivity to nicotine: implications for genetic research on nicotine dependence. Behav Genet 1995; 25: 16177.
  • 7
    Kozlowski L. T., Harford M. R. On the significance of never using a drug: an example from cigarette smoking. J Abnorm Psychol 1976; 85: 4334.
  • 8
    Pomerleau O. F., Collins A. C., Shiffman S., Pomerleau C. S. Why some people smoke and others do not: new perspectives. J Consult Clin Psychol 1993; 61: 72331.
  • 9
    Larson P. S., Silvette H. Tobacco: Experimental and Clinical Studies: Supplement I. Baltimore, MD: Williams & Wilkins Co.; 1968.
  • 10
    Pomerleau C. S., Pomerleau O. F. Euphoriant effects of nicotine in smokers. Psychopharmacology 1992; 108: 4605.
  • 11
    Yu H., Matsubayashi H., Amano T., Cai J., Sasa M. Activation by nicotine of striatal neurons receiving excitatory input from the substantia nigra via dopamine release. Brain Res 2000; 872: 2236.
  • 12
    Marks M. J., Stitzel J. A., Collins A. C. Genetic influences on nicotine responses. Pharmacol Biochem Behav 1989; 33: 66778.
  • 13
    Schechter M. D., Meehan S. M., Schechter J. B. Genetic selection for nicotine activity in mice correlates with conditioned place preference. Eur J Pharmacol 1995; 279: 5964.
  • 14
    Perkins K. A., Lerman C., Coddington S., Jetton C., Karelitz J. L., Wilson A. et al. Gene and gene by sex associations with initial sensitivity to nicotine in nonsmokers. Behav Pharmacol 2008; 19: 63040.
  • 15
    Acosta M. C., Eissenberg T., Nichter M., Nichter M., Balster R. L. Characterizing early cigarette use episodes in novice smokers. Addict Behav 2008; 33: 10621.
  • 16
    Kandel D. B., Hu M., Griesler P. C., Schaffran C. On the development of nicotine dependence in adolescence. Drug Alcohol Depend 2007; 91: 2639.
  • 17
    Chen X., Stacy A., Zheng H., Shan J., Spruijt-Metz D., Unger J. B. et al. Sensations from initial exposure to nicotine predicting adolescent smoking in China: a potential measure of vulnerability to nicotine. Nicotine Tob Res 2003; 5: 45563.
  • 18
    Johnson J. L., Tucker R. S., Ratner P. A., Bottorff J. L., Prkachin K. M., Shoveller J. et al. Socio-demographic correlates of cigarette smoking among high school students: results from the British Columbia youth survey on smoking and health. Can J Public Health 2004; 95: 26871.
  • 19
    Johnson J. L., Ratner P. A., Tucker R. S., Bottorff J. L., Zumbo B., Prkachin K. M. et al. Development of a multidimensional measure of tobacco dependence in adolescence. Addict Behav 2005; 30: 50115.
  • 20
    Centers for Disease Control. Cigarette smoking among adults—United States 2000. MMWR 2002; 51: 6425.
  • 21
    Muthén L. K., Muthén B. O. Mplus Version 4 [computer software]. 1998–2006.
  • 22
    Muthén L. K., Muthén B. O. Mplus User's Guide, 4th edn. Los Angeles, CA: Muthén and Muthén; 19982006.
  • 23
    Browne M. W., Cudeck R. Alternative ways of assessing model fit. Sociol Meth Res 1992; 21: 23058.
  • 24
    Hu L., Bentler P. M. Cutoff criteria for fit indexes in covariance structure analysis: conventional criteria versus new alternatives. Struct Equat Model 1999; 6: 155.
  • 25
    Jacquard J. Interaction Effects in Logistic Regression. Thousand Oaks, CA: Sage Publications; 2001.
  • 26
    Chen J. J. Communicating complex information: the interpretation of statistical interaction in multiple regression analysis. Am J Public Health 2003; 93: 13767.
  • 27
    Rodriguez D., Audrain-McGovern J. Construct validity analysis of the early smoking experience questionnaire for adolescents. Addict Behav 2004; 29: 10537.
  • 28
    O'Connor R. J., Kozlowski L. T., Vandenbergh D. J., Strasser A. A., Grant M. D., Vogler G. P. An examination of early smoking experiences and smoking status in a national cross-sectional sample. Addiction 2005; 100: 13527.
  • 29
    Perkins K. A., Grobe J. E., Fonte C., Goettler J., Caggiula A. R., Reynolds W. A. et al. Chronic and acute tolerance to subjective, behavioral and cardiovascular effects of nicotine in humans. J Pharmacol Exp Ther 1994; 270: 62838.
  • 30
    Pomerleau O. F., Pomerleau C. S., Mehringer A. M., Snedecor S. M., Cameron O. G. Validation of retrospective reports of early experiences with smoking. Addict Behav 2005; 30: 60711.
  • 31
    Dar R., Kaplan R., Shaham L., Frenk H. Euphoriant effects of nicotine in smokers: fact or artifact? Psychopharmacology (Berl) 2007; 191: 20310.
  • 32
    Piasecki T. M., McCarthy D. E., Fiore M. C., Baker T. B. Alcohol consumption, smoking urge, and the reinforcing effects of cigarettes: an ecological study. Psychol Addict Behav 2008; 22: 2309.