Elevated overdose mortality rates among First Nations individuals in a Canadian setting: a population-based analysis
Article first published online: 6 SEP 2010
© 2010 The Authors, Addiction © 2010 Society for the Study of Addiction
Volume 105, Issue 11, pages 1962–1970, November 2010
How to Cite
Milloy, M.-J., Wood, E., Reading, C., Kane, D., Montaner, J. and Kerr, T. (2010), Elevated overdose mortality rates among First Nations individuals in a Canadian setting: a population-based analysis. Addiction, 105: 1962–1970. doi: 10.1111/j.1360-0443.2010.03077.x
- Issue published online: 6 OCT 2010
- Article first published online: 6 SEP 2010
- Submitted 15 February 2010; initial review completed 22 March 2010; final version accepted 27 April 2010
- First Nations;
Aims To determine the total burden of illicit drug overdose mortality over the study period in the province of British Columbia and investigate possible population-level determinants by estimating rates among subgroups including First Nations individuals.
Design Review of coroner case files.
Setting The province of British Columbia, Canada.
Participants Individuals dying from an illicit drug overdose between 2001 and 2005.
Measurements Age-adjusted mortality rates, standardized mortality ratios (SMR) and years of potential life lost (YPLL), stratified by major population groups.
Findings Over the study period, 909 individuals died from illicit drug overdoses, including 104 (11.4%) First Nations individuals. Compared to the general population, First Nations males and females suffered from substantially elevated SMR and YPLL. In a multivariate logistic regression analysis, First Nations deaths were significantly more likely to be among women, related to injection drug use and to have occurred in the Downtown Eastside area of Vancouver, the local epicentre of human immunodeficiency virus infection and open drug use (all P < 0.05).
Conclusions This report found highly elevated overdose death rates and levels of premature mortality among First Nations Canadians in British Columbia compared to the general population. While previously unidentified, these findings are consistent with the poorer population health profile of First Nations Canadians. Although further research is needed to identify the causes of the elevated death rates, our findings support increased availability of evidence-based overdose prevention measures.