Diminished aversive classical conditioning in pathological gamblers
Article first published online: 8 MAY 2012
© 2012 The Authors, Addiction © 2012 Society for the Study of Addiction
Volume 107, Issue 9, pages 1660–1666, September 2012
How to Cite
Brunborg, G. S., Johnsen, B. H., Mentzoni, R. A., Myrseth, H., Molde, H., Lorvik, I. M., Bu, E. T. H. and Pallesen, S. (2012), Diminished aversive classical conditioning in pathological gamblers. Addiction, 107: 1660–1666. doi: 10.1111/j.1360-0443.2012.03891.x
- Issue published online: 2 AUG 2012
- Article first published online: 8 MAY 2012
- Accepted manuscript online: 19 MAR 2012 12:00AM EST
- Submitted 18 May 2011; initial review completed 9 August 2011; final version accepted 12 March 2012
- classical conditioning;
- pathological gambling;
Aims Impaired ability to form associations between negative events in gambling and aversive somatic reactions may be a predisposing factor for pathological gambling. The current study investigated whether a group of pathological gamblers and a control group differed in aversive classical conditioning.
Design A differential aversive classical conditioning paradigm, which consisted of three phases. In the habituation phase, one 850-Hz tone stimulus and one 1500-Hz tone stimulus were presented three times each in random order. In the acquisition phase, the two tones were presented 10 times each in random order, and one was always followed by a 100-dB burst of white noise. In the extinction phase the two tones were presented three times each without the white noise.
Setting University laboratory testing facilities and out-patient treatment facilities.
Participants Twenty pathological gamblers and 20 control participants.
Measurements Duration of seven cardiac interbeat-intervals (IBIs) following tone offset, gambling severity, tobacco and alcohol use, anxiety and depression.
Findings No group differences were found in the habituation and acquisition phases. However, a significant group × stimuli × trials × IBIs interaction effect was found in the extinction phase (P < 0.049). Follow-up analysis indicated that the pathological gamblers did not show aversive classical conditioning, but that the control group did.
Conclusions Pathological gamblers have a diminished capacity to form associations between aversive events and stimuli that predict aversive events. Aversion learning is likely to be an ineffective treatment for pathological gamblers.