Advances in understanding recessive resistance to plant viruses

Authors

  • JUAN A. DIAZ-PENDON,

    1. Estación Experimental ‘La Mayora’, Consejo Superior de Investigaciones Científicas, 29750 Algarrobo-Costa, Málaga, Spain
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    • Present address: Department of Plant Pathology, University of California, Riverside 900 University Avenue, Riverside, CA 92521, USA.

  • VERONICA TRUNIGER,

    1. Centro de Edafología y Biología Aplicada del Segura (CEBAS), Consejo Superior de Investigaciones Científicas, Campus Universitario de Espinardo, 30100 Espinardo, Murcia, Spain
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  • CRISTINA NIETO,

    1. Centro de Edafología y Biología Aplicada del Segura (CEBAS), Consejo Superior de Investigaciones Científicas, Campus Universitario de Espinardo, 30100 Espinardo, Murcia, Spain
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  • JORDI GARCIA-MAS,

    1. Laboratori CSIC-IRTA de Genètica Molecular Vegetal, Departament de Genètica Vegetal IRTA, Carretera de Cabrils s/n, 08348 Cabrils, Barcelona, Spain
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  • ABDELHAFID BENDAHMANE,

    1. INRA-URGV, 2 Rue Gaston Crémieux CP 5708, 91057 Evry Cedex, France
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  • MIGUEL A. ARANDA

    Corresponding author
    1. Centro de Edafología y Biología Aplicada del Segura (CEBAS), Consejo Superior de Investigaciones Científicas, Campus Universitario de Espinardo, 30100 Espinardo, Murcia, Spain
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* Correspondence: Miguel A. Aranda, Centro de Edafología y Biología Aplicada del Segura (CEBAS), Consejo Superior de Investigaciones Científicas, Apdo. Correos 164, 30100 Espinardo, Murcia, Spain. Tel.: +34 968396355; Fax: +34 968396213; E-mail: m.aranda@cebas.csic.es

SUMMARY

Recent work carried out to characterize recessive mutations which render experimental hosts non-permissive to viral infection (loss-of-susceptibility mutants) seems to be converging with new data on natural recessive resistance in crop species, and also with functional analyses of virus avirulence determinants. Perhaps the most well known examples are the studies that identified the eukaryotic translation initiation factors 4E(iso) (eIF(iso)4E) and 4E(eIF4E) as the host factors required for potyvirus multiplication within experimental and natural hosts, respectively, and the potyviral genome-linked protein (VPg) as the viral factor that directly interacts with eIF4E to promote potyvirus multiplication. The purpose of this paper is to review the available information on the characterization of loss-of-susceptibility mutants in experimental hosts, natural recessive resistances and virus avirulence factors, and also to comment on possible implications for the design of new sources of sustainable virus resistance.

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