• 1
    Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1984; 8390: 13115.
  • 2
    Taylor DN, Parsonnet J. The epidemiology and natural history of Helicobacter pylori infection. In: BlaserMJ, SmithPD, RavdinJI, GreenbergHB, GuerrantRL, eds. Infections of the Gastrointestinal Tract. New York: Raven Press, 1995: 55164.
  • 3
    Marshall BJ, Windsor HM. The relation of Helicobacter pylori to gastric adenocarcinoma and lymphoma: pathophysiology, epidemiology, screening, clinical presentation, treatment, and prevention. Med Clin North Am 2005; 89: 31344.
  • 4
    Perez-Perez GI, Rothenbacher D, Brenner H. Epidemiology of Helicobacter pylori infection. Helicobacter 2004; 9(Suppl. 1): 16.
  • 5
    Vera JF, Gotteland M, Chavez E, et al. Sucrose permeability in children with gastric damage and Helicobacter pylori infection. J Pediatr Gastroenterol Nutr 1997; 24: 50611.
  • 6
    Crowe SE. Helicobacter infection, chronic inflammation, and the development of malignancy. Curr Opin Gastroenterol 2005; 21: 328.
  • 7
    Gotteland M, Corvalan A, Sarmiento F, et al. Gastric permeability is not increased in children colonized by CagA-positive strains of Helicobacter pylori. Dig Liver Dis 2001; 33: 7504.
  • 8
    Marteau P, Minekus M, Havenaar R, Huis in't Veld JH. Survival of lactic acid bacteria in a dynamic model of the stomach and small intestine: validation and the effects of bile. J Dairy Sci 1997; 80: 10317.
  • 9
    Conway PL, Gorbach SL, Goldin BR. Survival of lactic acid bacteria in the human stomach and adhesion to intestinal cells. J Dairy Sci 1987; 70: 112.
  • 10
    Sherman LA, Savage DC. Lipoteichoic acids in Lactobacillus strains that colonize the mouse gastric epithelium. Appl Environ Microbiol 1986; 52: 3024.
  • 11
    Valeur N, Engel P, Carbajal N, Connolly N, Ladefoged K. Colonization and immunomodulation by Lactobacillus reuteri ATCC 55730 in the human gastrointestinal tract. Appl Environ Microbiol 2004; 70: 117681.
  • 12
    Elliott SN, Buret A, McKnight W, Miller MJ, Wallace JL. Bacteria rapidly colonize and modulate healing of gastric ulcers in rats. Am J Physiol 1998; 275(Pt 1): G42532.
  • 13
    Alsahli M, Michetti P. Lactobacilli for the management of Helicobacter pylori. Nutrition 2001; 17: 2689.
  • 14
    Garrido D, Suau A, Pochart P, Cruchet S, Gotteland M. Modulation of the fecal microbiota by the intake of a Lactobacillus johnsonii La1-containing product in human volunteers. FEMS Microbiol Lett 2005; 248: 24956.
  • 15
    Servin AL, Coconnier MH. Adhesion of probiotic strains to the intestinal mucosa and interaction with pathogens. Best Pract Res Clin Gastroenterol 2003; 17: 74154.
  • 16
    Sartor RB. Probiotic therapy of intestinal inflammation and infections. Curr Opin Gastroenterol 2005; 21: 4450.
  • 17
    Salminen S, Isolauri E, Salminen E. Clinical uses of probiotics for stabilizing the gut mucosal barrier: successful strains and future challenges. Antonie Van Leeuwenhoek 1996; 70: 34758.
  • 18
    Ling WH, Korpela R, Mykkanen H, Salminen S, Hanninen O. Lactobacillus strain GG supplementation decreases colonic hydrolytic and reductive enzyme activities in healthy female adults. J Nutr 1994; 124: 1823.
  • 19
    Marteau P, Flourie B, Pochart P, Chastang C, Desjeux JF, Rambaud JC. Effect of the microbial lactase (EC activity in yoghurt on the intestinal absorption of lactose: an in vivo study in lactase-deficient humans. Br J Nutr 1990; 64: 719.
  • 20
    Bhatia SJ, Kochar N, Abraham P, Nair NG, Mehta AP. Lactobacillus acidophilus inhibits growth of Campylobacter pylori in vitro. J Clin Microbiol 1989; 27: 232830.
  • 21
    Midolo PD, Lambert JR, Hull R, Luo F, Grayson ML. In vitro inhibition of Helicobacter pylori NCTC 11637 by organic acids and lactic acid bacteria. J Appl Bacteriol 1995; 79: 4759.
  • 22
    Aiba Y, Suzuki N, Kabir AM, Takagi A, Koga Y. Lactic acid-mediated suppression of Helicobacter pylori by the oral administration of Lactobacillus salivarius as a probiotic in a gnotobiotic model. Am J Gastroenterol 1998; 93: 2097101.
    Direct Link:
  • 23
    Sgouras D, Maragkoudakis P, Petraki K, et al. In vitro and in vivo inhibition of Helicobacter pylori by Lactobacillus casei strain Shirota. Appl Environ Microbiol 2004; 70: 51826.
  • 24
    Oh Y, Osato MS, Han X, Bennett G, Hong WK. Folk yoghurt kills Helicobacter pylori. J Appl Microbiol 2002; 93: 10838.
  • 25
    Tsai CC, Huang LF, Lin CC, Tsen HY. Antagonistic activity against Helicobacter pylori infection in vitro by a strain of Enterococcus faecium TM39. Int J Food Microbiol 2004; 96: 112.
  • 26
    Pinchuk IV, Bressollier P, Verneuil B, et al. In vitro anti-Helicobacter pylori activity of the probiotic strain Bacillus subtilis 3 is due to secretion of antibiotics. Antimicrob Agents Chemother 2001; 45: 315661.
  • 27
    Collado MC, Gonzalez A, Gonzalez R, Hernandez M, Ferrus MA, Sanz Y. Antimicrobial peptides are among the antagonistic metabolites produced by Bifidobacterium against Helicobacter pylori. Int J Antimicrob Agents 2005; 25: 38591.
  • 28
    Kim TS, Hur JW, Yu MA, et al. Antagonism of Helicobacter pylori by bacteriocins of lactic acid bacteria. J Food Prot 2003; 66: 312.
  • 29
    Lorca GL, Wadstrom T, Valdez GF, Ljungh A. Lactobacillus acidophilus autolysins inhibit Helicobacter pylori in vitro. Curr Microbiol 2001; 42: 3944.
  • 30
    Michetti P, Dorta G, Wiesel PH, et al. Effect of whey-based culture supernatant of Lactobacillus acidophilus (johnsonii) La1 on Helicobacter pylori infection in humans. Digestion 1999; 60: 2039.
  • 31
    Dalmau M, Maier E, Mulet N, Vinas M, Benz R. Bacterial membrane injuries induced by lactacin F and nisin. Int Microbiol 2002; 5: 7380.
  • 32
    Coconnier MH, Lievin V, Hemery E, Servin AL. Antagonistic activity against Helicobacter infection in vitro and in vivo by the human Lactobacillus acidophilus strain LB. Appl Environ Microbiol 1998; 64: 457380.
  • 33
    Kabir AM, Aiba Y, Takagi A, Kamiya S, Miwa T, Koga Y. Prevention of Helicobacter pylori infection by lactobacilli in a gnotobiotic murine model. Gut 1997; 41: 4955.
  • 34
    Johnson-Henry KC, Mitchell DJ, Avistzur Y, Galindo-Mata E, Jones NL, Sherman PM. Probiotics reduce bacterial colonization and gastric inflammation in H. pylori-infected mice. Dig Dis Sci 2004; 49: 1095102.
  • 35
    Ushiyama A, Tanaka K, Aiba Y, et al. Lactobacillus gasseri OLL2716 as a probiotic in clarythromycin-resistant Helicobacter pylori infection. J Gastroenterol Hepatol 2003; 18: 98691.
  • 36
    Uchida M, Kurakazu K. Yogurt containing Lactobacillus gasseri OLL2716 exerts gastroprotective action against acute gastric lesion and antral ulcer in rats. J Pharmacol Sci 2004; 96: 8490.
  • 37
    Nagaoka M, Hasimoto S, Watanabe T, Yokokura T, Mori Y. Anti-ulcer effects of lactic acid bacteria and their cell wall polysaccharides. Biol Pharm Bull 1994; 17: 10127.
  • 38
    Gotteland M, Cruchet S, Verbeke S. Effect of Lactobacillus ingestion on the gastrointestinal mucosal barrier alterations induced by indomethacin in humans. Aliment Pharmacol Ther 2001; 15: 117.
  • 39
    Mack DR, Michail S, Wei S, McDougall L, Hollingsworth MA. Probiotics inhibit enteropathogenic E. coli adherence in vitro by inducing intestinal mucin gene expression. Am J Physiol 1999; 276: G94150.
  • 40
    Songisepp E, Kullisaar T, Hutt P, et al. A new probiotic cheese with antioxidative and antimicrobial activity. J Dairy Sci 2004; 87: 201723.
  • 41
    Hamilton-Miller JMT. The role of probiotics in the treatment and prevention of Helicobacter pylori infection. Int J Antimicrob Agents 2003; 22: 3606.
  • 42
    Canducci F, Armuzzi A, Cremonini F, et al. A lyophilized and inactivated culture of Lactobacillus acidophilus increases Helicobacter pylori eradication rates. Aliment Pharmacol Ther 2000; 14: 16259.
  • 43
    Armuzzi A, Cremonini F, Ojetti V, et al. Effect of Lactobacillus GG supplementation on antibiotic-associated gastrointestinal side-effects during Helicobacter pylori eradication therapy: a pilot study. Digestion 2001; 63: 17.
  • 44
    Sheu BS, Wu JJ, Lo CY, et al. Impact of supplement with Lactobacillus- and Bifidobacterium-containing yogurt on triple therapy for Helicobacter pylori eradication. Aliment Pharmacol Ther 2002; 16: 166975.
  • 45
    Cremonini F, Di Caro S, Covino M, et al. Effect of different probiotic preparations on anti-Helicobacter pylori therapy-related side effects: a parallel group, triple blind, placebo-controlled study. Am J Gastroenterol 2002; 97: 27449.
    Direct Link:
  • 46
    Felley CP, Corthesy-Theulaz I, Rivero JL, et al. Favourable effect of an acidified milk (LC-1) on Helicobacter pylori gastritis in man. Eur J Gastroenterol Hepatol 2001; 13: 259.
  • 47
    Tursi A, Brandimarte G, Giorgetti GM, Modeo ME. Effect of Lactobacillus casei supplementation on the effectiveness and tolerability of a new second-line 10-day quadruple therapy after failure of a first attempt to cure Helicobacter pylori infection. Med Sci Monit 2004; 10: CR6626.
  • 48
    Cruchet S, Obregon MC, Salazar G, Diaz E, Gotteland M. Effect of the ingestion of a dietary product containing Lactobacillus johnsonii La1 on Helicobacter pylori colonization in children. Nutrition 2003; 19: 71621.
  • 49
    Gotteland M, Cruchet S. Suppressive effect of frequent ingestion of Lactobacillus johnsonii La1 on Helicobacter pylori colonization in asymptomatic volunteers. J Antimicrob Chemother 2003; 51: 13179.
  • 50
    Pantoflickova D, Corthesy-Theulaz I, Dorta G, et al. Favourable effect of regular intake of fermented milk containing Lactobacillus johnsonii on Helicobacter pylori associated gastritis. Aliment Pharmacol Ther 2003; 18: 80513.
  • 51
    Wang K-J, Li S-L, Liu C-S, et al. Effects of ingesting Lactobacillus- and Bifidobacterium-containing yogurt in subjects with colonized Helicobacter pylori. Am J Clin Nutr 2004; 80: 73741.
  • 52
    Gotteland M, Poliak L, Cruchet S, Brunser O. Effect of regular ingestion of Saccharomyces boulardii plus inulin or Lactobacillus acidophilus in children colonised by Helicobacter pylori. Acta Paediatr 2005; 94: 174751.
  • 53
    Wendakoon CN, Thomson ABR, Ozimek L. Lack of therapeutic effect of a specially designed yogurt for the eradication of Helicobacter pylori. Digestion 2002; 65: 1620.
  • 54
    Cats A, Kuipers EJ, Boschaert MA, Pot RG, Vandenbroucke-Grauls CM, Custers JG. Effect of frequent consumption of a Lactobacillus casei-containing milk drink in Helicobacter pylori-colonized subjects. Aliment Pharmacol Ther 2003; 17: 42935.
  • 55
    Sakamoto I, Igarashi M, Kimura K, Takagi A, Miwa T, Koga Y. Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans. J Antimicrob Chemother 2001; 47: 70910.
  • 56
    Shimizu T, Haruna H, Hisada K, Yamashiro Y. Effects of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in children. J Antimicrobial Chemother 2002; 50: 6178.
  • 57
    Daroch F, Hoeneisen M, Gonzalez CL, et al. In vitro antibacterial activity of Chilean red wines against Helicobacter pylori. Microbios 2001; 104: 7985.
  • 58
    Limuro M, Shibata H, Kawamori T, et al. Suppressive effects of garlic extract on Helicobacter pylori-induced gastritis in Mongolian gerbils. Cancer Lett 2002; 187: 618.
  • 59
    Burger O, Weiss E, Sharon N, Tabak M, Neeman I, Ofek I. Inhibition of Helicobacter pylori adhesion to human gastric mucus by a high-molecular weight constituent of cranberry juice. Crit Rev Food Sci Nutr 2002; 42(Suppl.): 27984.
  • 60
    Lengsfeld C, Deters A, Faller G, Hensel A. High molecular weight polysaccharides from black currant seeds inhibit adhesion of Helicobacter pylori to human gastric mucosa. Planta Med 2004; 70: 6206.
  • 61
    Chatterjee A, Yasmin T, Bagchi D, Stohs S. Inhibition of Helicobacter pylori in vitro by various berry extracts, with enhanced susceptibility to clarythromycin. Mol Cell Biochem 2004; 265: 1926.
  • 62
    Zhang L, Ma J, Pan K, Go VLW, Chen J, You W. Efficacy of cranberry juice on Helicobacter pylori infection: a double-blind, randomized placebo-controlled trial. Helicobacter 2005; 10: 13945.
  • 63
    Horie K, Horie N, Abdou AM, et al. Suppressive effect of functional drinking yogurt containing specific egg yolk immunoglobulin on Helicobacter pylori in humans. J Dairy Sci 2004; 87: 40739.
  • 64
    Di Mario F, Aragona G, Dal Bo N, et al. Use of bovine lactoferrin for Helicobacter pylori eradication. Dig Liver Dis 2003; 35: 70610.
  • 65
    Ushida Y, Shimokawa Y, Matsumoto H, Toida T, Hayasawa H. Effects of bovine alpha-lactalbumin on gastric defense mechanisms in naive rats. Biosci Biotechnol Biochem 2003; 67: 57783.
  • 66
    Brody EP. Biological activities of bovine glycomacropeptide. Br J Nutr 2000; 84(Suppl. 1): S3946.