• 1
    Talley NJ, Lauritsen K, Tunturi-Hihnala H, et al. Esomeprazole 20 mg maintains symptom control in endoscopy-negative gastro-oesophageal reflux disease: a controlled trial of ‘on-demand’ therapy for 6 months. Aliment Pharmacol Ther 2001; 15: 34754.
  • 2
    Johnson DA, Benjamin SB, Vakil NB, et al. Esomeprazole once daily for 6 months is effective therapy for maintaining healed erosive esophagitis and for controlling gastroesophageal reflux disease symptoms: a randomised, double-blind, placebo-controlled study of efficacy and safety. Am J Gastroenterol 2001; 96: 2734.
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  • 3
    Meineche-Schmidt V, Juhl HH, Ostergaard JE, et al. Costs and efficacy of three different esomeprazole treatment strategies for long-term management of gastro-esophageal reflux symptoms in primary care. Aliment Pharmacol Ther 2004; 19: 90715.
  • 4
    Dent J, Brun J, Fendrick AM, et al. An evidence-based appraisal of reflux disease management – the Genval Workshop Report. Gut 1998; 44: 116.
  • 5
    Zacny J, Zamakhshary M, Sketris I, Veldhuyzen van Zanten S. Systematic review: The efficacy of intermittent and on-demand therapy with histamine H2-receptor antagonists or proton pump inhibitors for gastro-oesophageal reflux disease patients. Aliment Pharmacol Ther 2205; 21: 1299312.
  • 6
    Donnellan C, Sharma N, Preston C, Moayyedi P. Medical treatments for the maintenance therapy of reflux oesophagitis and endoscopic negative reflux disease. Cochrane Database Syst Rev 2005; 18: CD003245.
  • 7
    Chren MM, Landefeld CS. Physicians’ behaviour and their interaction with drug companies. A controlled study of physicians who requested additions to a hospital drug formulary. JAMA 1994; 271: 6849.
  • 8
    Jones MI, Greenfield SM, Bradley CP. Prescribing new drugs: qualitative study of influences on consultants and general practitioners. BMJ 2001; 323: 17.
  • 9
    Armstrong D, Reyburn H, Jones R. A study of general practitioners’ reason for changing their prescribing behaviour. BMJ 1996; 12: 94952.
  • 10
    Schmock GT, Walton SM, Park HY, et al. Factors that influence prescribing decisions. Ann Phermacother 2004; 38: 55762.
  • 11
    Taylor RJ, Bond CM. Change in the established prescribing habits of general practitioners: an analysis of initial prescriptions in general practice. Br J Gen Pract 1991; 41: 2448.
  • 12
    Webb S, Lloyd M. Prescribing and referral in general practice: a study of patients’ expectations and doctors’ action. Br J Gen Pract 1994; 44: 1659.
  • 13
    Andersen M, Kragstrup J, Sondergaard J. How conducting a clinical trial affects physicians’ guideline adherence and drug preference. JAMA 2006; 295: 275964.