• 1
    Stroud M, Duncan H, Nightingale J. Guidelines for enteral feeding in adult hospital patients. Gut 2003; 52 (Suppl. 7): vii112.
  • 2
    Pearce CB, Duncan HD. Enteral feeding. Nasogastric, nasojejunal, percutaneous endoscopic gastrostomy, or jejunostomy: its indications and limitations. Postgrad Med J 2002; 78: 198204.
  • 3
    Ha MA, Jarvis MC, Mann JI. A definition for dietary fibre. Eur J Clin Nutr 2000; 54: 8614.
  • 4
    Lunn J, Buttriss JL. Carbohydrates and dietary fibre. Br Nutr Found Nutr Bull 2007; 32: 2164.
  • 5
    Rastall RA, Gibson GR, Gill HS, et al. Modulation of the microbial ecology of the human colon by probiotics, prebiotics and synbiotics to enhance human health: an overview of enabling science and potential applications. FEMS Microbiol Ecol 2005; 52: 14552.
  • 6
    Cummings JH. The effect of dietary fibre on fecal weight and composition. In: SpillerGA, ed. Handbook of Dietary Fibre in Human Nutrition. Tampa, Florida: CRC Press LLC, 2001: 183251.
  • 7
    Wiesen P, Van Gossum A, Preiser JC. Diarrhoea in the critically ill. Curr Opin Crit Care 2006; 12: 14954.
  • 8
    Shankardass K, Chuchmach S, Chelswick K, et al. Bowel function of long-term tube-fed patients consuming formulae with and without dietary fibre. JPEN J Parenter Enteral Nutr 1990; 14: 50812.
  • 9
    Kapadia SA, Raimundo AH, Grimble GK, Aimer P, Silk DB. Influence of three different fibre-supplemented enteral diets on bowel function and short-chain fatty acid production. JPEN J Parenter Enteral Nutr 1995; 19: 638.
  • 10
    Alam NH, Meier R, Rausch T, et al. Effects of a partially hydrolyzed guar gum on intestinal absorption of carbohydrate, protein and fat: a double-blind controlled study in volunteers. Clin Nutr 1998; 17: 1259.
  • 11
    Spaeth G, Gottwald T, Hirner A. Fibre is an essential ingredient of enteral diets to limit bacterial translocation in rats. Eur J Surg 1995; 161: 5138.
  • 12
    Folino M, McIntyre A, Young GP. Dietary fibres differ in their effects on large bowel epithelial proliferation and fecal fermentation-dependent events in rats. J Nutr 1995; 125: 15218.
  • 13
    Rehman KU, Wingertzahn MA, Teichberg S, Harper RG, Wapnir RA. Gum arabic (GA) modifies paracellular water and electrolyte transport in the small intestine. Dig Dis Sci 2003; 48: 75560.
  • 14
    Sobotka L, Bratova M, Slemrova M, Manak J, Vizd’a J, Zadak Z. Inulin as the soluble fibre in liquid enteral nutrition. Nutrition 1997; 13: 215.
  • 15
    Whelan K, Judd PA, Preedy VR, Simmering R, Jann A, Taylor MA. Fructooligosaccharides and fibre partially prevent the alterations in fecal microbiota and short-chain fatty acid concentrations caused by standard enteral formula in healthy humans. J Nutr 2005; 135: 1896902.
  • 16
    James SL, Muir JG, Curtis SL, Gibson PR. Dietary fibre: a roughage guide. Intern Med J 2003; 33: 2916.
  • 17
    Yang G, Wu X-T, Zhou Y, Wang Y-L. Application of dietary fibre in clinical enteral nutrition: a meta-analysis of randomised controlled trials. World J Gastroenterol 2005; 11: 39358.
  • 18
    Del Olmo D, Lopez del Val T, Martinez de Icaya P, et al. La fibre en nutricion enteral: revision sistematica de la literatura. Nutr Hosp 2004; 19: 16774.
  • 19
    Higgins JPT, Green S. eds. Cochrane Handbook for Systematic Reviews of Interventions 4.2.5 [updated May 2005].
  • 20
    Moher D, Cook DJ, Eastwood S, Olkin I, Rennie D, Stroup DF. Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. Quality of reporting of meta-analyses. Lancet 1999; 354: 1896900.
  • 21
    Jadad AR, Moore RA, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996; 17: 112.
  • 22
    Agency for Health Care Policy and Research. Acute Pain Management: operative or medical procedures and trauma. [article online], 1992.
  • 23
    Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003; 327: 55760.
  • 24
    Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002; 21: 153958.
  • 25
    Hayashino Y, Noguchi Y, Fukui T. Systematic evaluation and comparison of statistical tests for publication bias. J Epidemiol 2005; 15: 23543.
  • 26
    Macaskill P, Walter SD, Irwig L. A comparison of methods to detect publication bias in meta-analysis. Stat Med 2001; 20: 64154.
  • 27
    Tolia V, Ventimiglia J, Kuhns L. Gastrointestinal tolerance of a paediatric fibre formula in developmentally disabled children. J Am Coll Nutr 1997; 16: 2248.
  • 28
    De Kruif JT, Vos A. The influence of soyfibre supplemented tube feeding on the occurrence of diarrhoea in postoperative patients. Clin Nutr 1993; 12: 3604.
  • 29
    Reese JL, Means ME, Hanrahan K, Clearman B, Colwill M, Dawson C. Diarrhoea associated with nasogastric feedings. Oncol Nurs Forum 1996; 23: 5966; discussion 66–8.
  • 30
    Dobb GJ, Towler SC. Diarrhoea during enteral feeding in the critically ill: a comparison of feeds with and without fibre. Intensive Care Med 1990; 16: 2525.
  • 31
    Spapen H, Diltoer M, Van Malderen C, Opdenacker G, Suys E, Huyghens L. Soluble fibre reduces the incidence of diarrhoea in septic patients receiving total enteral nutrition: a prospective, double-blind, randomized, and controlled trial. Clin Nutr 2001; 20: 3015.
  • 32
    Schultz AA, Ashby-Hughes B, Taylor R, Gillis DE, Wilkins M. Effects of pectin on diarrhoea in critically ill tube-fed patients receiving antibiotics. Am J Crit Care 2000; 9: 40311.
  • 33
    Rushdi TA, Pichard C, Khater YH. Control of diarrhoea by fibre-enriched diet in ICU patients on enteral nutrition: a prospective randomized controlled trial. Clin Nutr 2004; 23: 134452.
  • 34
    Lampe JW, Effertz ME, Larson JL, Slavin JL. Gastrointestinal effects of modified guar gum and soy polysaccharide as part of an enteral formula diet. JPEN J Parenter Enteral Nutr 1992; 16: 53844.
  • 35
    Schneider SM, Girard-Pipau F, Anty R, et al. Effects of total enteral nutrition supplemented with a multi-fibre mix on faecal short-chain fatty acids and microbiota. Clin Nutr 2006; 25: 8290.
  • 36
    Grant LP, Wanger LI, Neill KM. Fibre-fortified feedings in immobile patients. Clin Nurs Res 1994; 3: 16672.
  • 37
    Belknap D, Davidson LJ, Smith CR. The effects of psyllium hydrophilic mucilloid on diarrhoea in enterally fed patients. Heart Lung 1997; 26: 22937.
  • 38
    Homann HH, Kemen M, Fuessenich C, Senkal M, Zumtobel V. Reduction in diarrhoea incidence by soluble fibre in patients receiving total or supplemental enteral nutrition. JPEN J Parenter Enteral Nutr 1994; 18: 48690.
  • 39
    Frankenfield DC, Beyer PL. Soy-polysaccharide fibre: effect on diarrhoea in tube-fed, head-injured patients. Am J Clin Nutr 1989; 50: 5338.
  • 40
    Hart GK, Dobb GJ. Effect of a fecal bulking agent on diarrhoea during enteral feeding in the critically ill. JPEN J Parenter Enteral Nutr 1988; 12: 4658.
  • 41
    Trier E, Wells JCK, Thomas AG. Effects of a mutifibre supplemented paediatric enteral feed on gastrointestinal function. J Paediatr Gastroenterol Nutr 1999; 28: 595.
  • 42
    Patil DH, Grimble GK, Keohane P, Attrill H, Love M, Silk DB. Do fibre containing enteral diets have advantages over existing low residue diets? Clin Nutr 1985; 4: 6771.
  • 43
    Meier R, Beglinger C, Schneider H, Rowedder A, Gyr K. Effect of a liquid diet with and without soluble fibre supplementation on intestinal transit and cholecystokinin release in volunteers. JPEN J Parenter Enteral Nutr 1993; 17: 2315.
  • 44
    Taper LJ, Milam RS, McCallister MS, Bowen PE, Thye FW. Mineral retention in young men consuming soy-fibre-augmented liquid-formula diets. Am J Clin Nutr 1988; 48: 30511.
  • 45
    Slavin JL, Nelson NL, McNamara EA, Cashmere K. Bowel function of healthy men consuming liquid diets with and without dietary fibre. JPEN J Parenter Enteral Nutr 1985; 9: 31721.
  • 46
    Silk DB, Walters ER, Duncan HD, Green CJ. The effect of a polymeric enteral formula supplemented with a mixture of six fibres on normal human bowel function and colonic motility. Clin Nutr 2001; 20: 4958.
  • 47
    Zimmaro DM, Rolandelli RH, Koruda MJ, Settle RG, Stein TP, Rombeau JL. Isotonic tube feeding formula induces liquid stool in normal subjects: reversal by pectin. JPEN J Parenter Enteral Nutr 1989; 13: 11723.
  • 48
    Fussell ST, Garmhause L, Koruda MJ. The influence of guar gum on diarrhoea in critically-ill tube-fed patients. J Parenter Enteral Nutr 1996; 20 (Suppl.): 26S.
  • 49
    Heather DJ, Howell L, Montana M, Howell M, Hill R. Effect of a bulk-forming cathartic on diarrhoea in tube-fed patients. Heart Lung 1991; 20: 40913.
  • 50
    Khalil L, Ho KH, Png D, Ong CL. The effect of enteral fibre-containing feeds on stool parameters in the post-surgical period. Singapore Med J 1998; 39: 1569.
  • 51
    Van Aerde J, Alarcon P, Lam W, et al. Tolerance and safety of energy-dense enteral formulae for young children. Int Pediatr 2003; 18: 959.
  • 52
    Fischer M, Adkins W, Hall L, Scaman P, Hsi S, Marlett J. The effects of dietary fibre in a liquid diet on bowel function of mentally retarded individuals. J Ment Defic Res 1985; 29 (Pt 4): 37381.
  • 53
    Zarling EJ, Edison T, Berger S, Leya J, DeMeo M. Effect of dietary oat and soy fibre on bowel function and clinical tolerance in a tube feeding dependent population. J Am Coll Nutr 1994; 13: 5658.
  • 54
    Vandewoude MF, Paridaens KM, Suy RA, Boone MA, Strobbe H. Fibre-supplemented tube feeding in the hospitalised elderly. Age Ageing 2005; 34: 1204.
  • 55
    Frascio F, Giacosa A, Sukkar SG, et al. Effetti delle fibre di soia sulla funzione intestinale in corso di nutrizione enterale. Riv Ital Nutr Parenterale Enterale 1994; 12: 905.
  • 56
    Cockram DB, Hensley MK, Rodriguez M, et al. Safety and tolerance of medical nutritional products as sole sources of nutrition in people on hemodialysis. J Ren Nutr 1998; 8: 2533.
  • 57
    Liu J, Xia Q. Relationship of dietary fibre and early enteral nutrition with digestive complications after surgical treatment of gastric cancer. Chin J Gastrointest Surg 2005; 8: 2235.
  • 58
    Heymsfield SB, Roongspisuthipong C, Evert M, Casper K, Heller P, Akrabawi SS. Fibre supplementation of enteral formulae: effects on the bioavailability of major nutrients and gastrointestinal tolerance. JPEN J Parenter Enteral Nutr 1988; 12: 26573.
  • 59
    Ren JA, Li JS, Jiang J, Xu BH, Gu J, Wang XB. Dietary fibre increases the postoperative patients’ colon mucosa proliferation: a prospective randomised clinical trial. Clin Nutr 1999; 18 (Suppl. 1): 23.
  • 60
    Richardson RA, Garden OJ, Carr K, Burns HJG, Shenkin A. Clinical and biochemical comparison of a standard versus a fibre containing enteral regimen. Clin Nutr 1987; 6: 37 (abstract O.58).
  • 61
    Kies C, Sanchez VE, Fox HM. Cellulose supplementation of a nutritionally complete, liquid formula diet: effect on gastrointestinal tract function of humans and fecal fibre recovery. J Food Sci 1984; 49: 8156.
  • 62
    Lübke HJ, Wienbeck M, Laslo KH, Frieling T. Bowel motor function during standardised diets differing in fibre content and consistency. Clin Nutr 1987; 6: 38.
  • 63
    Hofman Z, Drunen J, Brinkman JG, Valerio PG. Tolerance and efficacy of a multi-fibre enriched tube-feed in paediatric burn patients. Clin Nutr 2001; 20 (Suppl. 1): 63.
  • 64
    Guenter PA, Settle RG, Perlmutter S, Marino PL, DeSimone GA, Rolandelli RH. Tube feeding-related diarrhoea in acutely Ill patients. JPEN J Parenter Enteral Nutr 1991; 15: 27780.
  • 65
    Nakao M, Ogura Y, Satake S, et al. Usefulness of soluble dietary fibre for the treatment of diarrhoea during enteral nutrition in elderly patients. Nutrition 2002; 18: 359.
  • 66
    Liebl BH, Fischer MH, Van Calcar SC, Marlett JA. Dietary fibre and long-term large bowel response in enterally nourished nonambulatory profoundly retarded youth. JPEN J Parenter Enteral Nutr 1990; 14: 3715.
  • 67
    Matzkies F, Webs B. Wirkung einer neuen Sondennahrung auf den Stoffwechsel, die Urinelektrolyte und den Gastrointestinaltrakt beim gesunden Erwachsenen mit und ohne Zulage eines Ballaststoffes aus Sojakleie. Z Ernaehrungswiss 1985; 24: 10512.
  • 68
    Lozano Quintana MJ, Sanchez-Izquierdo Riera JA. Evaluation of the complications of the use of enteral diet with fibre in critical patients. Nutr Hosp 1991; 6: 37580.
  • 69
    Monypenny FC. Does fibre help reduce the incidence of diarrhoea in the enterally fed neurosurgical intensive care patient? Anaesth Intens Care 1989; 17: 223.
  • 70
    Grogan J, Watling R, Davey T, et al. Gastrointestinal effects of two fibre enriched paediatric enteral tube feeds – a pilot study. J Hum Nutr Diet 2006; 19: 462.
  • 71
    Van Calcar SC, Liebl BH, Fischer MH, Marlett JA. Long-term nutritional status of an enterally nourished institutionalized population. Am J Clin Nutr 1989; 50: 38190.
  • 72
    Vlcek G, Kies C, Fox HM. Calcium and phosphorus utilisation of human adults from a fibre enriched liquid formula diet. Fed Proc 1982; 41: 771.
  • 73
    DeVries JW. On defining dietary fibre. Proc Nutr Soc 2003; 62: 3743.
  • 74
    Sharp SJ, Thompson SG. Analysing the relationship between treatment effect and underlying risk in meta-analysis: comparison and development of approaches. Stat Med 2000; 19: 325174.
  • 75
    Johanson JF. Review of the treatment options for chronic constipation. MedGenMed 2007; 9: 25.
  • 76
    Wong JM, De Souza R, Kendall CW, Emam A, Jenkins DJ. Colonic health: fermentation and short chain fatty acids. J Clin Gastroenterol 2006; 40: 23543.
  • 77
    Livesey G, Elia M. Short chain fatty acids as an energy source in the colon: metabolism and clinical implications. In: CummingsJH, RombeauJL, SakataT, eds. Physiological and Clinical Aspects of Short Chain Fatty Acids. Cambridge: Cambridge University Press, 1995: 142782.
  • 78
    Elia M, Cummings JH. Physiological aspects of energy metabolism and gastrointestinal effects of carbohydrates. Eur J Clin Nutr 2007; 61 (Suppl. 1): 54074.
  • 79
    Bourlioux P. What is currently known about the molecular mechanisms of colonisation resistance. Anaerobe 1997; 3: 17984.
  • 80
    Hill MJ, Drasar BS. The normal colonic bacterial flora. Gut 1975; 16: 31823.
  • 81
    Levy J. The effects of antibiotic use on gastrointestinal function. Am J Gastroenterol 2000; 95 (Suppl. 1): S810.
  • 82
    Barbut F, Meynard JL. Managing antibiotic-associated diarrhoea. BMJ 2002; 324: 13456.
  • 83
    Bergogne-Berezin E. Treatment and prevention of antibiotic-associated diarrhoea. Int J Antimicrob Agents 2000; 16: 5216.
  • 84
    Surawicz CM. Antibiotic-associated diarrhoea and pseudomembranous colitis: are they less common with poorly absorbed antimicrobials? Chemotherapy 2005; 51 (Suppl. 1): 819.
  • 85
    Mitsui R, Karaki SI, Kubo Y, Sugiura Y, Kuwahara A. Fibre-free diet leads to impairment of neuronally mediated muscle contractile response in rat distal colon. Neurogastroenterol Motil 2006; 18: 1093101.
  • 86
    Silk DB. Fibre and enteral nutrition. Gut 1989; 30: 24664.
  • 87
    Jenkins DJ, Kendall CW, Vuksan V, et al. The effect of wheat bran particle size on laxation and colonic fermentation. J Am Coll Nutr 1999; 18: 33945.
  • 88
    Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrate, Fibre, Fat, Fatty Acids, Protein, and Amino Acids. Washington, DC: The National Academies Press, 2005.
  • 89
    Naaeder SB, Evans DF, Archampong EQ. Effect of acute dietary fibre supplementation on colonic pH in healthy volunteers. West Afr J Med 1998; 17: 1536.
  • 90
    Bourquin LD, Titgemeyer EC, Fahey GC Jr. Vegetable fibre fermentation by human fecal bacteria: cell wall polysaccharide disappearance and short-chain fatty acid production during in vitro fermentation and water-holding capacity of unfermented residues. J Nutr 1993; 123: 8609.
  • 91
    Khan KM, Edwards CA. In vitro fermentation characteristics of a mixture of Raftilose and guar gum by human faecal bacteria. Eur J Nutr 2005; 44: 3716.
  • 92
    Green CJ. Fibre in enteral nutrition. Clin Nutr 2001; 20 (Suppl. 1): 239.