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Clinical trial: pilot study of metformin for the treatment of non-alcoholic steatohepatitis

  1. R. LOOMBA1,
  2. G. LUTCHMAN1,
  3. D. E. KLEINER2,
  4. M. RICKS3,
  5. J. J. FELD1,
  6. B. B. BORG1,
  7. A. MODI1,
  8. P. NAGABHYRU1,
  9. A. E. SUMNER3,
  10. T. J. LIANG1,
  11. J. H. HOOFNAGLE1

Article first published online: 9 OCT 2008

DOI: 10.1111/j.1365-2036.2008.03869.x

Issue

Alimentary Pharmacology & Therapeutics

Alimentary Pharmacology & Therapeutics

Volume 29, Issue 2, pages 172–182, January 2009

Additional Information

How to Cite

LOOMBA, R., LUTCHMAN, G., KLEINER, D. E., RICKS, M., FELD, J. J., BORG, B. B., MODI, A., NAGABHYRU, P., SUMNER, A. E., LIANG, T. J. and HOOFNAGLE, J. H. (2009), Clinical trial: pilot study of metformin for the treatment of non-alcoholic steatohepatitis. Alimentary Pharmacology & Therapeutics, 29: 172–182. doi: 10.1111/j.1365-2036.2008.03869.x

Author Information

  1. 1

    Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

  2. 2

    Laboratory of Pathology, National Cancer Institute

  3. 3

    Clinical Endocrinology Branch, NIDDK, National Institutes of Health (NIH), Bethesda, MD, USA

*Dr J. H. Hoofnagle, Liver Disease Research Branch, NIH, Bldg 31, Room 9A27, 31 Center Drive, Bethesda, MD 20892, USA. E-mail: hoofnaglej@extra.niddk.nih.gov

Publication History

  1. Issue published online: 16 DEC 2008
  2. Article first published online: 9 OCT 2008
  3. Publication data Submitted 9 September 2008 First decision 27 September 2008 Resubmitted 30 September 2008 Resubmitted 1 October 2008 Accepted 2 October 2008 Epub Accepted Article 9 October 2008

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Appendix  S1. Protocol used to evaluate insulin sensitivity and imaging and anthropometric measures.

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