• 1
    Rockall TA, Logan RF, Devlin HB, et al. Incidence of and mortality from acute upper gastrointestinal haemorrhage in the United Kingdom. Steering Committee and members of the National Audit of Acute Upper Gastrointestinal Haemorrhage. BMJ 1995; 311: 2226.
  • 2
    Kapur KC, Green JT, Turner RG, et al. Auditing mortality from upper gastrointestinal haemorrhage: impact of a high dependency unit. J R Coll Physicians Lond 1998; 32: 24650.
  • 3
    Massó González EL, García Rodríguez LA. Proton pump inhibitors reduce the long-term risk of recurrent upper gastrointestinal bleeding: an observational study. Aliment Pharmacol Ther 2008; 28: 62937.
  • 4
    Bhatt DL, Scheiman J, Abraham NS, et al. ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use. Am J Gastroenterol 2008; 103: 2890907.
    Direct Link:
  • 5
    Lanas A, García-Rodríguez LA, Arroyo MT, et al. Effect of antisecretory drugs and nitrates on the risk of ulcer bleeding associated with nonsteroidal anti-inflammatory drugs, antiplatelet agents, and anticoagulants. Am J Gastroenterol 2007; 102: 50715.
  • 6
    Dall M, Schaffalitzky de Muckadell OB, Lassen AT, et al. An association between selective serotonin reuptake inhibitor use and serious upper gastrointestinal bleeding. Clin Gastroenterol Hepatol 2009; 7: 131421.
  • 7
    WHO Collaborating Centre for Drug Statistics Methodology. ATC index with DDDs and guidelines for ATC classification and DDD assignment. Oslo: Norwegian Institute of Public Health, 2006.
  • 8
    Gaist D, Sørensen HT, Hallas J. The Danish Prescription Registries. Dan Med Bull 1997; 44: 4458.
  • 9
    Frank L. Epidemiology. When an entire country is a cohort. Science 2000; 287: 23989.
  • 10
    Hallas J, Dall M, Andries A, et al. Use of single and combined antithrombotic therapy and risk of serious upper gastrointestinal bleeding: population based case-control study. BMJ 2006; 333: 726.
  • 11
    Johnsen SP, Sørensen HT, Mellemkjoer L, et al. Hospitalisation for upper gastrointestinal bleeding associated with use of oral anticoagulants. Thromb Haemost 2001; 86: 5638.
  • 12
    de Abajo FJ, Montero D, Rodríguez LA, et al. Antidepressants and risk of upper gastrointestinal bleeding. Basic Clin Pharmacol Toxicol 2006; 98: 30410.
  • 13
    Release 10.1. StataCorp, 4905 Lakeway Drive, College Station, TX, USA. Available at:
  • 14
    Hernández-Díaz S, Rodríguez LA. Association between nonsteroidal anti-inflammatory drugs and upper gastrointestinal tract bleeding/perforation: an overview of epidemiologic studies published in the 1990s. Arch Intern Med 2000; 160: 20939.
  • 15
    Chin MW, Yong G, Bulsara MK, et al. Predictive and protective factors associated with upper gastrointestinal bleeding after percutaneous coronary intervention: a case-control study. Am J Gastroenterol 2007; 102: 24116.
    Direct Link:
  • 16
    Ibáñez L, Vidal X, Vendrell L, et al. Upper gastrointestinal bleeding associated with antiplatelet drugs. Aliment Pharmacol Ther 2006; 23: 23542.
  • 17
    Sung JJ, Lau JY, Ching JY, et al. Continuation of low-dose aspirin therapy in peptic ulcer bleeding: a randomized trial. Ann Intern Med 2010; 152: 19.
  • 18
    Coté GA, Norvell JP, Rice JP, et al. Use of gastroprotection in patients discharged from hospital on nonsteroidal anti-inflammatory drugs. Am J Ther 2008; 15: 4449.
  • 19
    Targownik LE, Al-Mamfud A. The prevalence of risk factors for gastrointestinal complications and use of gastroprotection among persons hospitalized for cardiovascular disease. Aliment Pharmacol Ther 2006; 23: 7439.