• 1
    Guarino A, Albano F, Ashkenazi S, et al. European Society for Paediatric Gastroenterology, Hepatology, and Nutrition/European Society for Paediatric Infectious Diseases Evidence-based guidelines for management of acute gastroenteritis in children in Europe. J Pediatr Gastroenterol Nutr2008; 46: S81184.
  • 2
    AllenSJ, Martinez E, GregorioGV, DansLF. Probiotics for treating infectious diarrhea. Cochrane Database Syst Rev2010; 11:CD003048.
  • 3
    Szajewska H, Mrukowicz JZ. Probiotics in the treatment and prevention of acute infectious diarrhea in infants and children: a systematic review of published randomized, double-blind, placebo-controlled trials. J Pediatr Gastroenterol Nutr2001; 33(Suppl 2): S1725.
  • 4
    Van Niel CW, Feudtner C, Garrison MM, Christakis DA. Lactobacillus therapy for acute infectious diarrhea in children: a meta-analysis. Pediatrics 2002; 109: 67884.
  • 5
    Huang JS, Bousvaros A, Lee JW, Diaz A, Davidson EJ. Efficacy of probiotic use in acute diarrhea in children: a meta-analysis. Dig Dis Sci 2002; 47: 262534.
  • 6
    Szajewska H, Skorka A, Dylag M. Meta-analysis: saccharomyces boulardii for treating acute diarrhea in children. Aliment Pharmacol Ther 2007; 25: 25764.
  • 7
    Szajewska H, Skorka A, Ruszczynski M, Gieruszczak-Bialek D. Meta-analysis: Lactobacillus GG for treating acute diarrhea in children. Aliment Pharmacol Ther 2007; 25: 87181.
  • 8
    Berni Canani R, Cirillo P, Terrin G, et al. Probiotics for treatment of acute diarrhea in children: randomised clinical trial of five different preparations. BMJ 2007; 335: 3406.
  • 9
    Hummel AS, Hertel C, Holzapfel WH, Franz CM. Antibiotic resistances of starter and probiotic strains of lactic acid bacteria. Appl Environ Microbiol 2007; 73: 7309.
  • 10
    Kastner S, Perreten V, Bleuler H, Hugenschmidt G, Lacroix C, Meile L. Antibiotic susceptibility patterns and resistance genes of starter cultures and probiotic bacteria used in food. Syst Appl Microbiol 2006; 29: 14555.
  • 11
    Egervarn M, Danielsen M, Roos S, Lindmark H, Lindgren S. Antibiotic susceptibility profiles of Lactobacillus reuteri and Lactobacillus fermentum. J Food Prot 2007; 70: 4128.
  • 12
    Kayser FH. Safety aspects of enterococci from the medical point of view. Int J Food Microbiol 2003; 88: 25562.
  • 13
    Thomas DW, Greer FR, Committee on Nutrition, Section on Gastroenterology Hepatology, and Nutrition. Clinical report. Probiotics and prebiotics in pediatrics. Pediatrics 2010; 126: 121731.
  • 14
    Shavit I, Brant R, Nijssen-Jordan C, Galbraith R, Johnson DW. A novel imaging technique to measure capillary-refill time: improving diagnostic accuracy for dehydration in young children with gastroenteritis. Pediatrics 2006; 118: 24028.
  • 15
    Friedman JN, Goldman RD, Srivastava R, Parkin PC. Development of a clinical dehydration scale for use in children between 1 and 36 months of age. J Pediatr 2004; 145: 2017.
  • 16
    Grossi E, Buresta R, Abbiati R, Cerutti R. Clinical trial on the efficacy of a new symbiotic formulation, Flortec, in patients with acute diarrhea: a multicenter, randomized study in primary care. J Clin Gastroenterol 2010; 44: S3541.
  • 17
    FAO/WHO. Expert consultation on evaluation of health and nutritional properties of probiotics. FAO/WHO: Cordoba, 2001.
  • 18
    Caprioli A, Pezzella C, Morelli R, et al. Enteropathogens associated with childhood diarrhea in Italy. The Italian study group on gastrointestinal infections. Pediatr Infect Dis J 1996; 15: 87683.
  • 19
    Giaquinto C, Dominiak-Felden G, Van Damme P, et al. Summary of effectiveness and impact of rotavirus vaccination with the oral pentavalent rotavirus vaccine: a systematic review of the experience in industrialized countries. Hum Vaccin 2011; 7: 73448.
  • 20
    Vesikari T, Karvonen A, Prymula R, et al. Immunogenicity and safety of the human rotavirus vaccine Rotarix co-administered with routine infant vaccines following the vaccination schedules in Europe. Vaccine 2010; 28: 52729.
  • 21
    Saia M, Giliberti A, Callegaro G. Hospitalisation for rotavirus gastroenteritis in the paediatric population in the Veneto Region, Italy. BMC Public Health 2010; 10: 63640.
  • 22
    Guarino A, Lo Vecchio A, Berni Canani R. Probiotics as prevention and treatment for diarrhea. Curr Opinion Gastroenterol 2009; 25: 1823.
  • 23
    Preidis GA, Hill C, Guerrant RL, Ramakrishna BS, Tannock GW, Versalovic J. Probiotics, enteric and diarrheal diseases, and global health. Gastroenterology 2011; 140: 814.
  • 24
    Kadowaki N, Ho S, Antonenko S, et al. Subsets of human dendritic cell precursors express different Toll-like receptors and respond to different microbial antigens. J Exp Med 2001; 194: 8639.
  • 25
    Blum S, Schiffrin EJ. Intestinal microflora and homeostasis of the mucosal immune response: implications for probiotic bacteria? Curr Issues Intest Microbiol 2003; 4: 5360.
  • 26
    Sekirov I, Finlay BB. The role of the intestinal microbiota in enteric infection. J Physiol 2009; 587: 415967.
  • 27
    Militi E, Matteoli G, Iliev ID, Rescigno M. Comparison of the immunomodulatory properties of three probiotic strains of Lactobacilli using complex culture systems: prediction for in vivo efficacy. PLoS ONE 2009; 4: e7056.
  • 28
    Morelli L, Zonenschain D, Callegari ML, et al. Assessment of a new synbiotic preparation in healthy volunteers: survival, persistence of probiotic strains and its effect on the indigenous flora. Nutr J 2003; 2: 117.
  • 29
    Vandenplas Y, Brunser O, Szajewska H. Saccharomyces boulardii in childhood. Eur J Pediatr 2009; 168: 25365.
  • 30
    Sekirov I, Finlay BB. The role of the intestinal microbiota in enteric infection. J Physiol 2009; 17: 415967.
  • 31
    Ten Bruggencate SJ, Bovee-Oudenhoven IM, Lettink-Wissink ML, Van der Meer R. Dietary fructooligosaccharides dose-dependently increase translocation of salmonella in rats. J Nutr 2003; 133: 23138.
  • 32
    Cummings JH, Christie S, Cole TJ. A study of fructo oligosaccharides in the prevention of travellers diarrhoea. Aliment Pharmacol Ther 2001; 15: 113945.
  • 33
    Macfarlane GT, Steed H, Macfarlene S. Bacterial metabolism and health-related effects of galacto-oligosaccharides and other prebiotics. J Appl Microbiol 2008; 104: 30544.
  • 34
    Drakoularakou A, Tzortzis G, Rastall RA, Gibson GR. A double-blind, placebo-controlled, randomized human study assessing the capacity of a novel galacto-oligosaccharide mixture in reducing traveller's diarrhea. Eur J Clin Nutr 2010; 64: 14652.
  • 35
    Makelainen H, Saarinen M, Stowell J, Rautonen N, Ouwehand AC. Xylo-oligosaccharides and lactiotol promote the growth of Bifidobaterium lactis and Lactobacillus species in pure cultures. Benef Microbes 2010; 1: 13948.
  • 36
    Fontana M, Zuin G, Pancheri P, Fusco FC, Lambertini A, Berni Canani R, SIGEP Working Group on Intestinal Infections. Cost associated with outpatient diarrhea in infants and toddlers: a nationwide study of the Italian Society of Paediatric Gastroenterology and Hepatology (SIGEP). Dig Liver Dis 2004; 36: 5237.