PREGNANCY AND IBD
Patients' knowledge of pregnancy-related issues in inflammatory bowel disease and validation of a novel assessment tool (‘CCPKnow’)
Article first published online: 9 MAY 2012
© 2012 Blackwell Publishing Ltd
Alimentary Pharmacology & Therapeutics
Volume 36, Issue 1, pages 57–63, July 2012
How to Cite
Selinger, C. P., Eaden, J., Selby, W., Jones, D. B., Katelaris, P., Chapman, G., McDonald, C., McLaughlin, J., Leong, R. W. L. and Lal, S. (2012), Patients' knowledge of pregnancy-related issues in inflammatory bowel disease and validation of a novel assessment tool (‘CCPKnow’). Alimentary Pharmacology & Therapeutics, 36: 57–63. doi: 10.1111/j.1365-2036.2012.05130.x
- Issue published online: 1 JUN 2012
- Article first published online: 9 MAY 2012
- Manuscript Accepted: 22 APR 2012
- Manuscript Revised: 16 APR 2012
- Manuscript Revised: 10 APR 2012
- Manuscript Received: 21 MAR 2012
Inflammatory bowel diseases (IBD) require complex therapeutic decisions and life choices concerning pregnancy, but little is known about patient's knowledge of IBD and its treatment before and during pregnancy.
To develop a novel tool (Crohn's and Colitis Pregnancy Knowledge Score ‘CCPKnow’) to assess knowledge of pregnancy-related issues in IBD. The validated tool was then applied to determine knowledge in patients.
Discriminate ability of ‘CCPKnow’ was validated in four groups with different levels of IBD knowledge. Reliability and readability were tested by Cronbach-α and Flesch-Kencaid. Construct validity was subsequently assessed against general IBD knowledge (CCKnow) in 145 women with IBD. Associations between patient factors and knowledge were studied.
Median CCPKnow scores differed significantly between the validation groups (P < 0.001). CCPKnow displayed excellent internal consistency, reliability (Cronbach-α 0.94), readability (reading age 9 years) and close correlation with CCKnow (Spearman's ρ 0.64; P < 0.001). Of 145 patients, 44.8% had poor, 27.6% adequate, 17.3% good and only 10.3% very good knowledge. Better knowledge was associated with Caucasian ethnicity, higher income, having a partner, having children, Crohn's and Colitis Association membership, longer disease duration and Crohn's disease.
Crohn's and Colitis Pregnancy Knowledge Score, a novel knowledge assessment tool of pregnancy and IBD, demonstrated excellent test characteristics. We found that nearly half of the women with IBD had poor knowledge, identifying a pressing need for better education.