• 1
    Sainio S, Kekomaki R, Riikonen S, Teramo K. Maternal thrombocytopenia: a population based study. Acta Obstetricia et Gynecologica Scandinavica 2000; 79: 7449.
  • 2
    McCrae KR, Samuels P, Schreiber AD. Pregnancy associated thrombocytopenia: pathogenesis and management. Blood 1992; 80: 2697714.
  • 3
    Letsky E. Haemostasis in pregnancy. In: MorganBM, ed. Foundations of Obstetric Anaesthesia,. London: Farrand Press, 1987: 189207.
  • 4
    Gerbasi FR, Bottoms S, Farag A, Mammen E. Increased intravascular coagulation associated with pregnancy. Obstetrics and Gynecology 1990; 75: 3859.
  • 5
    Letsky E. The haematological system. In: HyttenF, ChamberlainG, eds. Clinical Physiology in Obstetrics, 2nd edn. Oxford: Blackwell Scientific Publications, 1991: 3941.
  • 6
    Hellgren M, Blomback M. Studies on blood coagulation and fibrinolysis in pregnancy, during delivery and in the puerperium. 1. Normal conditions. Gynecologic and Obstetric Investigation 1981; 21: 1416.
  • 7
    Gerbasi FR, Bottoms S, Farag A, Mammen EF. Changes in hemostasis activity during delivery and the immediate postpartum period. American Journal of Obstetrics and Gynecology 1990; 162: 115863.
  • 8
    Boehlen F, Hohlfeld H, Extermann P, Perneger TV, De Moerloose P. Platelet count at term pregnancy: a reappraisal of the threshold. Obstetrics and Gynecology 2000; 95: 2933.
  • 9
    Gill PR, Lind T, Walker W. Platelet values during normal pregnancy. British Journal of Obstetrics and Gynaecology 1985; 92: 4805.
  • 10
    Wallenburg HCS, Van Kessel PH. Platelet lifespan in normal pregnancy as determined by a non radioisotopic technique. British. Journal of Obstetrics and Gynaecology 1978; 85: 336.
  • 11
    Douglas JT, Shah M, Lowe GDO. Plasma fibrinopeptide A and beta-thromboglobulin in pre-eclampsia and pregnancy hypertension. Thrombosis and Haemostasis 1982; 47: 545.
  • 12
    Bonnar J, Davidson JF, Pidgeon CF, McNicols GP, Douglas AS. Fibrin degradation products in normal and abnormal pregnancy and parturition. British Medical Journal 1969; 3: 13740.
  • 13
    Bonnar J, McNicol GP, Douglas AS. Coagulation and fibrinolytic mechanisms during and after normal childbirth. British Medical Journal 1970; 2: 2003.
  • 14
    Bonnar J, Prentice CRM, McNicol GP, Douglas AS. Haemostatic mechanism in the uterine circulation during placental separation. British Medical Journal 1970; 2: 5647.
  • 15
    Burrows RF, Kelton JG. Thrombocytopenia at delivery: a prospective survey of 6715 deliveries. American Journal of Obstetrics and Gynecology 1990; 162: 7314.
  • 16
    Shehata N, Burrow RF, Kelton JG. Gestational thrombocytopenia. Clinical Obstetrics and Gynecology 1999; 42: 32734.
  • 17
    Morrison R, Crawford J, MacPherson M, Hepinstall S. Platelet behaviour in normal pregnancy, pregnancy complicated by essential hypertension and pregnancy induced hypertension. Thrombosis and Haemostasis 1985; 54: 60711.
  • 18
    Nicolini U, Guarneri D, Gianotti GA, Campagnoli C, Crosignani PG, Gatti L. Maternal and fetal platelet activation in normal pregnancy. Obstetrics and Gynecology 1994; 83: 659.
  • 19
    Burrows RF, Kelton JG. Incidentally detected thrombocytopenia in healthy mothers and their infants. New England Journal of Medicine 1988; 319: 1425.
  • 20
    American College of Obstetrics and Gynecology Committee on Practice Bulletins. American College of Obstetrics and Gynecology Practice Bulletin. Thrombocytopenia in pregnancy. International Journal of Gynaecology and Obstetrics 1999; 67: 11722.
  • 21
    Lescale KB, Eddelman KA, Cines DB, et al. Antiplatelet antibody testing in thrombocytopenic pregnant women. American Journal of Obstetrics and Gynecology 1996; 174: 10148.
  • 22
    Cines DG, Blanchette VS. Immune thrombocytopenic purpura. New England Journal of Medicine 2002; 346: 1325.
  • 23
    Boehler F, Hohlfeld P, Exterman P, De Moerloose P. Maternal antiplatelet antibodies in predicting risk of neonatal thrombocytopenia. Obstetrics and Gynecology 1999; 93: 16973.
  • 24
    Gill KK, Kelton JG. Management of idiopathic thrombocytopenic purpura in pregnancy. Seminars in Hematology 2000; 37: 27583.
  • 25
    Letsky EA, Greaves M. Guidelines on the investigation and management of thrombocytopenia in pregnancy and neonatal alloimmune thrombocytopenia. British Journal of Haematology 1996; 95: 2136.
  • 26
    Laros RK, Sweet RL. Management of idiopathic thrombocytopenic purpura during pregnancy. American Journal of Obstetrics and Gynecology 1975; 122: 1826.
  • 27
    Valat AS, Caulier MT, Devos P, et al. Relationships between severe neonatal thrombocytopenia and maternal characteristics in pregnancies associated with autoimmune thrombocytopenia. British Journal of Haematology 1998; 103: 397401.
  • 28
    Burrows RF, Kelton JG. Fetal thrombocytopenia and its relation to maternal thrombocytopenia. New England Journal of Medicine 1993; 329: 143666.
  • 29
    Godelieve V, Chritianens ML, Nieuwenhus HK, Bussel JB. Comparison of platelet counts in first and second newborns of mothers with immune thrombocytopenic purpura. Obstetrics and Gynecology 1997; 90: 54652.
  • 30
    Stamilio DM, Macones GA. Selection of delivery methods in pregnancies complicated by autoimmune thrombocytopenia: a decision analysis. Obstetrics and Gynecology 2002; 94: 417.
  • 31
    Cook RL, Miller RE, Katz VL, Cefalo RC. Immune thrombocytopenic purpura in pregnancy. a reappraisal of management. Obstetrics and Gynecology 1991; 78: 57883.
  • 32
    Kaha DJ, Richardson DK, Billett HH. Association of thrombocytopenia and delivery method with intraventricular haemorrhage among very-low-birth-weight. American Journal of Obstetrics and Gynecology 2002; 186: 10916.
  • 33
    Payne SD, Resnick R, Moore TR, Hedriana HL, Kelly TF. Maternal characteristics and risk of severe neonatal thrombocytopenia and intracranial hemorrhage in pregnancies complicated by autoimmune thrombocytopenia. American Journal of Obstetrics and Gynecology 1997; 177: 14955.
  • 34
    George JN, Woolf SH, Roskob GE, et al. Idiopathic thrombocytopenic purpura. a practice guideline developed by explicit methods for the American Society of Hematology. Blood 1996; 88: 340.
  • 35
    Lain KY, Roberts JM. Contemporary concepts of the pathogenesis and management of pre-eclampsia. Journal of American Medical Association 2002; 287: 31836.
  • 36
    Goldman-Wohl D, Yagel S. Regulation of trophoblast invasion. From normal implantation to pre-eclampsia. Molecular and Cellular Endocrinology 2002; 187: 2338.
  • 37
    Zhou Y, Damsky CH, Chiu K, Roberts JM, Fisher SJ. Pre-eclampsia is associated with abnormal expression of invasive cytotrophoblasts. Journal of Clinical Investigation 1993; 91: 95060.
  • 38
    Zhou Y, McMaster M, Woo K, et al. Vascular endothelial cell growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe pre-eclampsia and hemolysis, elevated liver enzymes and low platelets syndrome. American Journal of Pathology 2002; 160: 140523.
  • 39
    Redman CWG. Current topic: pre-eclampsia and the placenta. Placenta 1991; 12: 3018.
  • 40
    Burrows RF, Hunter DJ, Andrew M, Kelton JG. A prospective study investigating the mechanism of thrombocytopenia in pre-eclampsia. Obstetrics and Gynecology 1987; 70: 3348.
  • 41
    Zemel MB, Zemel PC, Berry S, et al. Altered platelet calcium metabolism as an early predictor of increased peripheral vascular resistance and pre-eclampsia in urban black women. New England Journal of Medicine 1990; 323: 4348.
  • 42
    Reubinoff BE, Schenker JG. HELLP syndrome − a syndrome of hemolysis, elevated liver enzymes and low platelet count-complicating pre-eclampsia/eclampsia. International Journal of Gynecology and Obstetrics 1991; 36: 95102.
  • 43
    Sibai BM. The HELLP Syndrome (hemolysis, elevated liver enzymes and low platelets). Much ado about nothing? American Journal of Obstetrics and Gynecology 1990; 162: 3116.
  • 44
    Caritis S, Sibai B, Hauth J, et al. National Institute of Child Health and Human Development network of maternal-fetal medicine units: Low dose aspirin to prevent pre-eclampsia in women at high risk. New England Journal of Medicine 1998; 338: 7015.
  • 45
    Martin JN, Files JC, Blake PG, Perry KG, Morrison JC, Norman PH. Post partum plasma exchange for atypical pre-eclampsia as HELLP (hemolysis, elevated liver enzymes and low platelets). American Journal of Obstetrics and Gynecology 1995; 172: 110712.
  • 46
    Martin JN, Perry KG, Blake PG, May WA, Moore A, Robinette L. Better maternal outcomes are achieved with postpartum HELLP. American Journal of Obstetrics and Gynecology 1997; 177; 110117.
  • 47
    Esplin MS, Branch DW. Diagnosis and management of thrombotic microangiopathies during pregnancy. Clinical Obstetrics and Gynecology 1999; 42: 3608.
  • 48
    Tsai HM, Lian ECY. Antibodies to von Willebrand factor cleaving protease in acute thrombotic thrombocytopenic purpura. New England Journal of Medicine 1998; 339: 158594.
  • 49
    Levy GG, Nichols WC, Lian EC, et al. Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature 2001; 413: 48894.
  • 50
    Weiner CP. Thrombotic microangiopathy in pregnancy and the post partum period. Seminars in Hematology 1987; 24: 11929.
  • 51
    Budman DR, Steinberg AD. Hematologic aspects of systemic lupus erythematosus. Annals of Internal Medicine 1977; 86: 2209.
  • 52
    Provost TT, Watson R, Gaither KK, Harley JB. The neonatal lupus erythematosus syndrome. Journal of Rheumatology 1987; 14: 199205.
  • 53
    Wilson WA, Gharavi AE, Koike T, et al. International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome. Arthritis and Rheumatism 1999; 42: 130911.
  • 54
    George JN, Raskob GE, Shah SR, et al. Drug-induced thrombocytopenia. A systematic review of published case reports. Annals of Internal Medicine 1998; 129: 88690.
  • 55
    Burlingame J, McGaraghan A, Kilpatrick S, Hambleforn J, Main E, Laros RK. Maternal and fetal outcomes in pregnancies affected by Von Willebrand disease type 2. American Journal of Obstetrics and Gynecology 2001; 184: 22930.
  • 56
    Letsky EA. Hemostasis and epidural anaesthesia. International Journal of Obstetric Anaesthesia 1991; 1: 514.
  • 57
    Yuen TST, Kua JSW, Tan IKS. Spinal haematoma following epidural anaesthesia in a patient with eclampsia. Anaesthesia 1999; 54: 3504.
  • 58
    Lao TT, Halpern SH, MacDonald D, Huh C. Spinal subdural haematoma in a parturient after attempted epidural anaesthesia. Canadian Journal of Anaesthesia 1993; 40: 3405.
  • 59
    Loo CC, Dahlgren G, Iresdedt L. Neurological complications in obstetric regional anaesthesia. International Journal of Obstetric Anaesthesia 2000; 9: 99124.
  • 60
    Bromage PR. Neurologic Complications of regional anaesthesia for obstetrics. In: SchniderSM, LevinsonG, eds. Anesthesia for Obstetrics, 3rd edn. Baltimore: Williams & Wilkins, 1993: 4434.
  • 61
    Rolbin SH, Abbott D, Musclow E, Papsin F, Lie LM, Freedman J. Epidural anaesthesia in pregnant women with low platelet counts. Obstetrics and Gynecology 1988; 71: 91820.
  • 62
    Rasmus KT, Rottman RL, Kotelko DM, Wright WC, Stone JJ, Rosenblatt RM. Unrecognised thrombocytopenia and regional anaesthesia in parturients: a retrospective review. Obstetrics and Gynecology 1989; 73: 9436.
  • 63
    Beilin YM, Zahn J, Comerford M. Safe epidural analgesia in thirty parturients with platelet counts between 69,000 and 98,000/μL. Anesthesia and Analgesia 1997; 85: 38590.
  • 64
    Beilin Y, Bodian CA, Haddad EM, Leibowitz AB. Practice patterns of anesthesiologists regarding situations in obstetric anesthesia where clinical management is controversial. Anesthesia and Analgesia 1996; 83: 73541.
  • 65
    Chrisopoulos CG, Machin SJ. A new type of pseudothrombocytopenia: EDTA-mediated aggregation of platelets bearing FAB fragments of a chimeric antibody. British Journal of Haematology 1994; 87: 6502.
  • 66
    Douglas MJ. Platelets, the parturient and regional anesthesia. International Journal of Obstetric Anaesthesia 2001; 10: 11320.
  • 67
    Simon L, Santi TM, Sacquin P, Hamza J. Pre-anaesthetic assessment of coagulation abnormalities in obstetric patients: Usefulness, timing and clinical implications. British Journal of Anaesthesia 1997; 78: 67883.
  • 68
    Orlikowski CEP, Rocke DA, Murray WB, et al. Thromboelastography changes in pre-eclampsia and eclampsia. British Journal of Anaesthesia 1996; 77: 15761.
  • 69
    Sharma SK, Philip J, Whitten CW, Padakandla UB, Landers DF. Assessment of changes in coagulation in parturients with pre-eclampsia using thromboelastography. Anesthesiology 1999; 90: 348590.
  • 70
    Mammen EF, Comp PC, Gosselin R, et al. PFA-100: a new method of assessment of platelet function. Seminars in Thrombosis and Hemostasis 1998; 24: 195202.
  • 71
    Vincelot A, Nathan N, Collet D, Mehaddi Y, Grandchamp P, Julia A. Platelet function during pregnancy: an evaluation using the PFA-100 analyser. British Journal of Anaesthesia 2001; 87: 8903.