Presented in part at the Euroanaesthesia 2010 congress, Helsinki; June 2010.
Reproducibility of non-standardised autonomic function testing in the pre-operative assessment screening clinic*
Article first published online: 22 NOV 2010
© 2010 The Authors. Anaesthesia © 2010 The Association of Anaesthetists of Great Britain and Ireland
Volume 66, Issue 1, pages 10–14, January 2011
How to Cite
Keet, S. W. M., Bulte, C. S. E., Boer, C. and Bouwman, R. A. (2011), Reproducibility of non-standardised autonomic function testing in the pre-operative assessment screening clinic. Anaesthesia, 66: 10–14. doi: 10.1111/j.1365-2044.2010.06566.x
- Issue published online: 16 DEC 2010
- Article first published online: 22 NOV 2010
- Accepted: 18 October 2010
By convention, autonomic function tests are undertaken under standard test conditions that limit their implementation during routine pre-operative assessment. We therefore evaluated the comparability of autonomic function tests under both non-standardised and standardised test conditions in 20 healthy male subjects. Autonomic function was assessed using an ECG monitor and a continuous non-invasive blood pressure measurement device. Under non-standardised conditions, intraclass correlation for heart rate variability analysis was good for the low and high frequency bands (0.87; 95% CI 0.58–0.96 and 0.83; 95% CI 0.56–0.94, respectively), but moderate (0.65; 95% CI 0.14–0.86) for the very low frequency band; reproducibility was high for the expiration/inspiration ratio (0.89; 95% CI 0.71–0.96), Valsalva ratio (0.76; 95% CI 0.37–0.91) and handgrip test (0.76; 95% CI 0.35–0.91) (all p < 0.05) but was low for the response to quick standing. Reproducibility under standardised conditions was comparable to the above values. We demonstrated that reproducibility for most autonomic tests under non-standardised conditions is acceptable and suggest that implementation of these tests during pre-operative assessment may be feasible.