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Animal Genetics
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Results of a whole-genome quantitative trait locus scan for growth, carcass composition and meat quality in a porcine four-way cross

Authors

  • N. Harmegnies,

    1. Unit of Animal Genomics, Faculty of Veterinary Medicine and Centre for Biomedical Integrative Genoproteomics, 20 Boulevard de Colonster, 4000 Liège, Belgium
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  • F. Davin,

    1. Unit of Animal Genomics, Faculty of Veterinary Medicine and Centre for Biomedical Integrative Genoproteomics, 20 Boulevard de Colonster, 4000 Liège, Belgium
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  • S. De Smet,

    1. Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Production, Ghent University, Proefhoevestraat 10, 9090 Melle, Belgium
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  • N. Buys,

    1. Division of Gene Technology, Department of Biosystems, Katholieke Universiteit Leuven, 30 Kasteelpark Arenberg, 3001 Leuven, Belgium
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  • M. Georges,

    1. Unit of Animal Genomics, Faculty of Veterinary Medicine and Centre for Biomedical Integrative Genoproteomics, 20 Boulevard de Colonster, 4000 Liège, Belgium
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  • W. Coppieters

    1. Unit of Animal Genomics, Faculty of Veterinary Medicine and Centre for Biomedical Integrative Genoproteomics, 20 Boulevard de Colonster, 4000 Liège, Belgium
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M. Georges, Unit of Animal Genomics, Faculty of Veterinary Medicine and Centre for Biomedical Integrative Genoproteomics, 20 Boulevard de Colonster, 4000 Liège, Belgium.
E-mail: michel.georges@ulg.ac.be

Summary

A whole-genome quantitative trait locus (QTL) scan for 31 phenotypes related to growth, carcass composition and meat quality was conducted using 1187 progeny of a commercial four-way cross. Animals were genotyped for 198 microsatellite markers that spanned the entire porcine genome. QTL analysis was conducted to extract information from paternal and maternal meioses separately using a rank-based nonparametric approach for half-sib designs. Nine QTL exceeded genome-wide significance: one QTL affecting growth (average daily gain on SSC1), two QTL influencing carcass composition (fatness on SSC3 and muscle mass on SSC15) and six QTL influencing meat quality (tenderness on SSC4 and SSC14; colour on SSC5, SSC6 and SSCX; and conductivity on SSC16). All but one of these coincided with previously reported QTL. In addition, we present evidence for 78 suggestive QTL with a combined false discovery rate of 40%.

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Article Information

DOI

10.1111/j.1365-2052.2006.01523.x

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Keywords

  • carcass composition;
  • growth;
  • meat quality;
  • pig;
  • quantitative trait loci

Publication History

  • Issue online:
  • Version of record online:
  • Accepted for publication 12 August 2006

Supporting Information

Table S1 Description of the analysed traits.

Table S2 Porcine marker map.

FilenameDescription
AGE1523TableS1.pdf18KSupporting info item
AGE1523TableS2.pdf21KSupporting info item

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