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Regional variations in community consumption of antibiotics in Hungary, 1996–2003

  1. Maria Matuz1,*,
  2. Ria Benko1,
  3. Peter Doro1,
  4. Edit Hajdu2,
  5. Gabor Nagy3,
  6. Erzsebet Nagy2,
  7. Dominique L. Monnet4,
  8. Gyongyver Soos1

Article first published online: 7 NOV 2005

DOI: 10.1111/j.1365-2125.2005.02525.x

Issue

British Journal of Clinical Pharmacology

British Journal of Clinical Pharmacology

Volume 61, Issue 1, pages 96–100, January 2006

Additional Information

How to Cite

Matuz, M., Benko, R., Doro, P., Hajdu, E., Nagy, G., Nagy, E., Monnet, D. L. and Soos, G. (2006), Regional variations in community consumption of antibiotics in Hungary, 1996–2003. British Journal of Clinical Pharmacology, 61: 96–100. doi: 10.1111/j.1365-2125.2005.02525.x

Author Information

  1. 1

    Department of Clinical Pharmacy and

  2. 2

    Department of Clinical Microbiology, University of Szeged and

  3. 3

    IMS PharmMIS Consulting Company, Budapest, Hungary, and

  4. 4

    National Centre for Antimicrobials and Infection Control, Statens Serum Institut, Copenhagen, Denmark

*Maria Matuz, Department of Clinical Pharmacy, University of Szeged, H-6725 Szeged, Szikra u. 8, Hungary. Tel.: + 36 62 54 4944 Fax: + 36 62 54 4921 E-mail: matuz@clph.szote.u-szeged.hu

Publication History

  1. Issue published online: 7 NOV 2005
  2. Article first published online: 7 NOV 2005
  3. Received 5 August 2005 Accepted 22 August 2005

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Keywords:

  • antibacterials;
  • community consumption;
  • determinants of antibiotic use;
  • drug utilization;
  • regional differences

Aims

To study regional differences and identify determinants of antibiotic consumption in ambulatory care in Hungary.

Methods

Regional distribution-based antibiotic sales data were converted into a number of defined daily doses (DDD) per 1000 inhabitant-days. Correlations were assessed with the Spearman rank test.

Results

There were large and stable interregional differences in antibiotic consumption. They were associated with socio-economic determinants, e.g. the population receiving free access to medicines and receiving regular social assistance.

Conclusions

More detailed studies are needed to better understand the determinants of antibiotic use in these specific patient populations and to identify additional determinants at regional level.

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