Potentially inappropriate prescribing in an Irish elderly population in primary care
Article first published online: 1 SEP 2009
© 2009 The Authors. Journal compilation © 2009 The British Pharmacological Society
British Journal of Clinical Pharmacology
Volume 68, Issue 6, pages 936–947, December 2009
How to Cite
Ryan, C., O'Mahony, D., Kennedy, J., Weedle, P. and Byrne, S. (2009), Potentially inappropriate prescribing in an Irish elderly population in primary care. British Journal of Clinical Pharmacology, 68: 936–947. doi: 10.1111/j.1365-2125.2009.03531.x
- Issue published online: 27 NOV 2009
- Article first published online: 1 SEP 2009
- Received 23 January 2009 Accepted14 August 2009
- 1Acove quality indicators. Ann Intern Med 2001; 135: 653–67., , , .
- 2Development and validation of an Improving Prescribing in the Elderly Tool. Can J Clin Pharmacol 2000; 7: 103–7., , , .
- 3A method for assessing drug therapy appropriateness. J Clin Epidemiol 1992; 45: 1045–51., , , , , , , .
- 4Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med 2003; 163: 2716–24., , , , , .
- 5STOPP screening tool of older person's prescriptions) and START (screening tool to alert doctors to right treatment). Consensus validation. Int J Clin Pharmacol Ther 2008; 46: 72–83., , , , .
- 6Inappropriate medications in the elderly. Clin Pharmacol Ther 2009; 85: 94–7., , , .
- 7Explicit criteria for determining inappropriate medication use in nursing home residents. UCLA Division of Geriatric Medicine. Arch Intern Med 1991; 151: 1825–32., , , , , .
- 8Explicit criteria for determining potentially inappropriate medication use by the elderly. An update. Arch Intern Med 1997; 157: 1531–6..
- 9Drug utilization and potentially inappropriate drug use in elderly residents of a community in Istanbul, Turkey. Int J Clin Pharmacol Ther 2005; 43: 195–202., , .
- 10Polypharmacy and potential inappropriateness of pharmacological treatment among community-dwelling elderly patients. Arch Gerontol Geriatr 2007; 44: 303–9., .
- 11Inappropriate drug prescribing in home-dwelling, elderly patients: a population-based survey. Arch Intern Med 2002; 162: 1707–12., , .
- 12Inappropriate drug prescribing in older adults: the updated 2002 Beers criteria – a population-based cohort study. Br J Clin Pharmacol 2005; 60: 137–44., , , , , , .
- 13Inappropriate drug use by Portuguese elderly outpatients – effect of the Beers criteria update. Pharm World Sci 2006; 28: 296–301., , , .
- 14Trends in potentially inappropriate prescribing amongst older UK primary care patients. Pharmacoepidemiol Drug Saf 2007; 16: 658–67., , , , , , .
- 15Potentially inappropriate medication use in the community-dwelling elderly: findings from the 1996 Medical Expenditure Panel Survey. JAMA 2001; 286: 2823–9., , , , , , .
- 16Inappropriate drug prescribing for the community-dwelling elderly. JAMA 1994; 272: 292–6., , .
- 17Potentially inappropriate medication use by elderly persons in U.S. Health Maintenance Organizations 2000–2001. J Am Geriatr Soc 2005; 53: 227–32., , , , , , , , .
- 18National Institute for Health and Clinical Excellence. Management of Hypertension in Adults in Primary Care. London: June 2006. Available at http://www.nice.org.uk/Guidance/CG34 (last accessed 5 August 2009).
- 19Inappropriate prescribing in the older population: need for new criteria. Age Ageing 2008; 37: 138–41., .
- 20Inappropriate prescribing in the elderly: a comparison of the Beers criteria and the improved prescribing in the elderly tool (IPET) in acutely ill elderly hospitalized patients. J Clin Pharm Ther 2006; 31: 617–26., , , .
- 21STOPP Screening Tool of Older Persons' potentially inappropriate Prescriptions): application to acutely ill elderly patients and comparison with Beers' criteria. Age Ageing 2008; 37: 673–9., .
- 22START screening tool to alert doctors to the right treatment) – an evidence-based screening tool to detect prescribing omissions in elderly patients. Age Ageing 2007; 36: 632–8., , , .
- 23The continuing challenge of inappropriate prescribing in the elderly: an update of the evidence. J Am Pharm Assoc 2002; 42: 847–57., .
- 24A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987; 40: 373–83., , , .
- 25Charlson Index comorbidity adjustment for ischemic stroke outcome studies. Stroke 2004; 35: 1941–5., , , .
- 26An adaptation of Charlson comorbidity index predicted subsequent mortality in a health survey. J Clin Epidemiol 2004; 57: 403–8., , , , , , .
- 27World Health Organisation (WHO) collaborating centre for drug statistics methodology. ATC classification Index with DDDs. 2008.
- 28Adverse drug reactions as cause of hospital admissions: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA). J Am Geriatr Soc 2002; 50: 1962–8., , , , , , .
- 29Preventable drug-related hospital admissions. Ann Pharmacother 2002; 36: 1238–48., , , .
- 30Inappropriate prescribing in older people. Rev Clin Gerontol 2008; 12: 65–76., .
- 31British National Formulary, 55th edn. London: BMA/RPSGB, 2008., ed.
- 32Intercollegiate Stroke Working Party. National Clinical Guideline for Stroke, 3rd edn. London: Royal College of Physicians Clinical Effectiveness & Evaluation Unit, Royal College of Physicians, 2008; 67–8.
- 33Second European Stroke Prevention Study: antiplatelet therapy is effective regardless of age. ESPS2 Working Group. Acta Neurol Scand 1999; 99: 54–60., , , , , , .
- 34Cost effective prescribing of proton pump inhibitors (PPI's) in the GMS scheme. Ir Med J 2005; 98: 78–80., , , .
- 35Hazardous benzodiazepine regimens in the elderly: effects of half-life, dosage, and duration on risk of hip fracture. Am J Psychiatry 2001; 158: 892–8., , , , .
- 36Educating physicians to reduce benzodiazepine use by elderly patients: a randomized controlled trial. CMAJ 2003; 168: 835–9., , , , , .
- 37Effectiveness of current treatment approaches for benzodiazepine discontinuation: a meta-analysis. Addiction 2009; 104: 13–24., , , , .
- 38Treatment with statins after acute myocardial infarction in patients > or =80 years: underuse despite general acceptance of drug therapy for secondary prevention. Pharmacoepidemiol Drug Saf 2006; 15: 261–7., , , .
- 39the OLDY (Old people Drug & DYsregulations) Study Group. Relationship between polypharmacy and underprescribing. Br J Clin Pharmacol 2008; 65: 130–3., , , ,
- 40Department of Health. Pharmacy in England – Building on Strengths – Delivering the Future. London: Department of Health, 2008.
- 41Department of Health. Medicines and Older People: Implementing Medicines Related Aspects of the National Service Framework for Older People. London: Department of Health, 2001.
- 42Does home based medication review keep older people out of hospital? The HOMER randomised controlled trial. BMJ 2005; 330: 293–7., , , , , , , , .
- 43Randomised controlled trial of clinical medication review by a pharmacist of elderly patients receiving repeat prescriptions in general practice. BMJ 2001; 323: 1340–3., , , , , .
- 44Home-based medication review in a high risk elderly population in primary care – the POLYMED randomised controlled trail. Age Aging 2007; 36: 292–7., , .
- 45Clinical medication review by a pharmacist of elderly people living in care homes – randomised controlled trial. Age Aging 2006; 35: 586–91., , , , , , .
- 46Pharmacist-led medication review in patients over 65: a randomized, controlled trial in primary care. Age Aging 2001; 30: 205–11., , , , , , , .