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Figure S1 Progression-free survival (PFS) probability according to the glutathione S-transferase (GST) π 105Ile[RIGHTWARDS ARROW]Val genotype. Median PFS was 7.36 months for Ile/Ile (56 patients, 53 events), 7.56 months for Ile/Val (49 patients, 46 events) and 9.76 months for Val/Val (12 patients, 12 events). Log rank test: P = 0.20 (P = 0.22 after adjustment on treatment arms)

Figure S2 Progression-free survival (PFS) probability according to the XPD 751Lys[RIGHTWARDS ARROW]Gln genotype. Median PFS was 6.38 months for Gln/Gln (16 patients, 16 events), 8.01 months for Lys/Gln (58 patients, 55 events) and 6.41 months for Lys/Lys (41 patients, 38 events). Log rank test: P = 0.33 (P = 0.29 after adjustment on treatment arms)

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