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Impact of CYP2D6, CYP3A5, CYP2C9 and CYP2C19 polymorphisms on tamoxifen pharmacokinetics in Asian breast cancer patients

  1. Joanne S. L. Lim1,3,
  2. Xiang A. Chen1,
  3. Onkar Singh1,
  4. Yoon S. Yap2,
  5. Raymond C. H. Ng2,
  6. Nan S. Wong2,
  7. Mabel Wong2,
  8. Edmund J. D. Lee3,
  9. Balram Chowbay1,*

Article first published online: 11 APR 2011

DOI: 10.1111/j.1365-2125.2011.03905.x

Issue

British Journal of Clinical Pharmacology

British Journal of Clinical Pharmacology

Special Issue: Drug allergy: themed section

Volume 71, Issue 5, pages 737–750, May 2011

Additional Information

How to Cite

Lim, J. S. L., Chen, X. A., Singh, O., Yap, Y. S., Ng, R. C. H., Wong, N. S., Wong, M., Lee, E. J. D. and Chowbay, B. (2011), Impact of CYP2D6, CYP3A5, CYP2C9 and CYP2C19 polymorphisms on tamoxifen pharmacokinetics in Asian breast cancer patients. British Journal of Clinical Pharmacology, 71: 737–750. doi: 10.1111/j.1365-2125.2011.03905.x

Author Information

  1. 1

    Laboratory of Clinical Pharmacology, Division of Medical Sciences, Humphrey Oei Institute of Cancer Research

  2. 2

    Department of Medical Oncology, National Cancer Centre

  3. 3

    Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore

*Assoc. Prof. Balram Chowbay PhD, Clinical Pharmacology Laboratory, Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre, 11 Hospital Drive, Singapore 169610. Tel.: + 65 6436 8321 Fax: + 65 6372 0161 E-mail: ctebal@nccs.com.sg

Publication History

  1. Issue published online: 11 APR 2011
  2. Article first published online: 11 APR 2011
  3. Accepted manuscript online: 11 JAN 2011 09:40AM EST
  4. Received , 21 September 2010, Accepted , 29 December 2010, Accepted Article , 11 January 2011

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