Translation Section


What do clinical pharmacologists do? A questionnaire survey of senior UK clinical pharmacologists inline image

Jeffrey K. Aronson

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Kava hepatotoxicity in traditional and modern use: the presumed Pacific kava paradox hypothesis revisited inline image

Rolf Teschke, Jerome Sarris & Isaac Schweitzer

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Positron emission tomography molecular imaging for drug development inline image

Paul M. Matthews, Eugenii A. Rabiner, Jan Passchier & Roger N. Gunn

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Pre-hypertension: how low to go and do drugs have a role? inline image

Gordon McInnes

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Junior doctors prescribing: enhancing their learning in practice inline image

Charlotte Rothwell, Bryan Burford, Jill Morrison, Gill Morrow, Maggie Allen, Carol Davies, Beate Baldauf, John Spencer, Neil Johnson, Ed Peile & Jan Illing

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Assessment of the cardiac safety of prucalopride in healthy volunteers: a randomized, double-blind, placebo- and positive-controlled thorough QT study inline image

Boaz Mendzelevski, Jannie Ausma, Dennis O. Chanter, Patricia Robinson, Rene Kerstens, Lieve Vandeplassche & John Camm

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Single dose pharmacokinetics, pharmacodynamics, tolerability and safety of BAY 60–5521, a potent inhibitor of cholesteryl ester transfer protein inline image

Michael-Friedrich Boettcher, Roland Heinig, Carsten Schmeck, Christian Kohlsdorfer, Matthias Ludwig, Anja Schaefer, Sabine Gelfert-Peukert, Georg Wensing & Olaf Weber

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Prediction of a potentially effective dose in humans for BAY 60-5521, a potent inhibitor of cholesteryl ester transfer protein (CETP) by allometric species scaling and combined pharmacodynamic and physiologically-based pharmacokinetic modeling inline image

Olaf Weber, Stefan Willmann, Hilmar Bischoff, Volkhart Li, Alexandros Vakalopoulos, Klemens Lustig, Frank-Thorsten Hafner, Roland Heinig, Carsten Schmeck & Klaus Buehner

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Pharmacokinetics, adverse effects and tolerability of a novel analogue of human pancreatic polypeptide, PP 1420 inline image

Tricia M. Tan, Benjamin C. T. Field, James S. Minnion, Joyceline Cuenco-Shillito, Edward S. Chambers, Sagen Zac-Varghese, Charlie J. Brindley, Shahrul Mt-Isa, Francesca Fiorentino, Deborah Ashby, Ian Ward, Mohammad A. Ghatei & Stephen R. Bloom

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Dosing algorithm to target a predefined AUC in patients with primary central nervous system lymphoma receiving high dose methotrexate inline image

Markus Joerger, Andrés J. M. Ferreri, Stephan Krähenbühl, Jan H. M. Schellens, Thomas Cerny, Emanuele Zucca & Alwin D. R. Huitema

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Prediction and evaluation of fetal toxicity induced by NSAIDs using transplacental kinetic parameters obtained from human placental perfusion studies inline image

Kyohei Shintaku, Satoko Hori, Hiroki Satoh, Kiyomi Tsukimori, Hitoo Nakano, Tomoyuki Fujii, Yuji Taketani, Hisakazu Ohtani & Yasufumi Sawada

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CYP2C8 but not CYP3A4 is important in the pharmacokinetics of montelukast inline image

Tiina Karonen, Pertti J. Neuvonen & Janne T. Backman

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Metabolic capabilities of cytochrome P450 enzymes in Chinese liver microsomes compared with those in Caucasian liver microsomes inline image

Junling Yang, Minxia M. He, Wei Niu, Steven A. Wrighton, Li Li, Yang Liu & Chuan Li

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Staggered overdose pattern and delay to hospital presentation are associated with adverse outcomes following paracetamol-induced hepatotoxicity inline image

Darren G. N. Craig, Caroline M. Bates, Janice S. Davidson, Kirsty G. Martin, Peter C. Hayes & Kenneth J. Simpson

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Clomipramine concentration and withdrawal symptoms in 10 neonates inline image

Peter G. J. ter Horst, Susanne van der Linde, Jan Pieter Smit, Jan den Boon, Richard A. van Lingen, Frank G. A. Jansman, Lolkje T. W. De Jong-van den Berg & Bob Wilffert

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The effects of a single nucleotide polymorphism in SLCO1B1 on the pharmacodynamics of pravastatin inline image

Nicholas G. Martin, Ka Wah Li, Heather Murray, Wendy Putt, Chris J. Packard & Steve E. Humphries

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