Fen Jiang and Zeruesenay Desta contributed equally to this work.
Methods in clinical pharmacology
Effects of clopidogrel and itraconazole on the disposition of efavirenz and its hydroxyl metabolites: exploration of a novel CYP2B6 phenotyping index
Version of Record online: 14 DEC 2012
© 2012 The Authors. British Journal of Clinical Pharmacology © 2012 The British Pharmacological Society
British Journal of Clinical Pharmacology
Volume 75, Issue 1, pages 244–253, January 2013
How to Cite
Jiang, F., Desta, Z., Shon, J.-H., Yeo, C.-W., Kim, H.-S., Liu, K.-H., Bae, S.-K., Lee, S.-S., Flockhart, D. A. and Shin, J.-G. (2013), Effects of clopidogrel and itraconazole on the disposition of efavirenz and its hydroxyl metabolites: exploration of a novel CYP2B6 phenotyping index. British Journal of Clinical Pharmacology, 75: 244–253. doi: 10.1111/j.1365-2125.2012.04314.x
- Issue online: 14 DEC 2012
- Version of Record online: 14 DEC 2012
- Accepted manuscript online: 3 MAY 2012 06:55AM EST
- Received; 29 September 2011; Accepted; 24 April 2012; Accepted Article Published Online; 3 May 2012
Table S1. Validation criteria for phenotyping metrics. Further desirable properties of phenotyping metrics.
Table S2. Demographics of study subjects, grouped according to CYP2B6*6 genotype. Data are presented as means ± SD. aP values among the three genotypes were determined using the Kruskal–Wallis test. BMI, body mass index.
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