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Figure S1

Funnel plots with pseudo 95% confidence limits for: (a) Effect of different classes of antihypertensive monotherapy vs. placebo on brachial systolic blood pressure (Figure 2); (b) Effect of different classes of antihypertensive monotherapy vs. placebo on central systolic blood pressure (Figure 3); (c) Effect of different combination of classes of antihypertensive drugs on placebo-adjusted differences between central systolic blood pressure and brachial systolic blood pressure (Figure 5); (d) Effect of antihypertensive monotherapy compared to placebo on augmentation index (Figure 6).

Figure S2

Effect of different classes of antihypertensive monotherapy on brachial systolic blood pressure (bSBP). Abbreviations: ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; BB, β-blocker; CCB, calcium channel blocker; D, thiazide diuretic; ES, effect size.

Figure S3

Effect of different classes of antihypertensive monotherapy on central systolic blood pressure (cSBP). Abbreviations: ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; BB, β-blocker; CCB, calcium channel blocker; D, thiazide diuretic; ES, effect size.

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