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Summary.— Thirty-four patients with lichen planus were treated in a double-blind trial in which either 500 mg of griseofulvin-FP or a placebo was issued to the patients on a random distribution basis. A significant difference was found between the results obtained with griseofulvin and those with the placebo. The favourable response to the treatment was accompanied by more or less typical histopathological features. No untoward effects, or recurrence in lesions were noted in the course of the trial.