Based on a paper read at the 1975 Meeting of the Investigative Group of the B.A.D.
Prostaglandins and pruritus*
Article first published online: 29 JUL 2006
British Journal of Dermatology
Volume 94, Issue 3, pages 273–275, March 1976
How to Cite
LOVELL, C.R., BURTON, P. A., DUNCAN, E. H.L. and BURTON, J.L. (1976), Prostaglandins and pruritus. British Journal of Dermatology, 94: 273–275. doi: 10.1111/j.1365-2133.1976.tb04383.x
- Issue published online: 29 JUL 2006
- Article first published online: 29 JUL 2006
- Accepted for publication 4 July 1975
We have found that pretreatment of human skin with prostaglandin El significantly lowers the threshold of human skin to itching evoked by both histamine and papain. Prostaglandins may thus potentiate pruritus in inflammatory skin disease, presumably by a non-specific effect on nerve-endings.