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The effect of clobetasone butyrate and other topical steriods on skin thickness of the domestic pig
Article first published online: 29 JUL 2006
DOI: 10.1111/j.1365-2133.1976.tb05144.x
1365-2133/asset/cover.gif?v=1&s=413074e1e506a67a21dcc4e2de9ff9b6ce256d16 "British Journal of Dermatology")
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How to Cite
WINTER, G. D. and WILSON, L. (1976), The effect of clobetasone butyrate and other topical steriods on skin thickness of the domestic pig. British Journal of Dermatology, 94: 545–550. doi: 10.1111/j.1365-2133.1976.tb05144.x
Publication History
- Issue published online: 29 JUL 2006
- Article first published online: 29 JUL 2006
- Accepted for publication 15 August 1975
- Abstract
- References
- Cited By
SUMMARY
A new glucocorticoid, clobetasone butyrate, has been shown in patients to have good topical anti-inflammatory activity and a minimal effect on hypothalamic–pituitary–adrenal function. Among a group of topically active corticosteroids, compared in a controlled study in the domestic pig, clobetasone butyrate is shown to cause less epidermal thinning than any of the others except only 1% hydrocortisone. This evidence of a lesser atrophogenic effect may indicate further dissociation of unwanted from wanted properties in clobetasone butyrate.