Severe oral lichen planus: treatment with an aromatic retinoid (etretinate)
Article first published online: 29 JUL 2006
British Journal of Dermatology
Volume 106, Issue 1, pages 77–80, January 1982
How to Cite
HERSLE, K., MOBACKEN, H., SLOBERG, K. and THILANDER, H. (1982), Severe oral lichen planus: treatment with an aromatic retinoid (etretinate). British Journal of Dermatology, 106: 77–80. doi: 10.1111/j.1365-2133.1982.tb00904.x
- Issue published online: 29 JUL 2006
- Article first published online: 29 JUL 2006
- Accepted for publication 5 March 1981
A double-blind study of twenty-eight patients with severe oral lichen planus treated with etretinate (75 mg daily) or a placebo for 2 months, showed that the oral retinoid had a marked beneficial effect. Nine non-responders who had received only placebo then entered an open cross-over study and they responded well to etretinate.
Etretinate thus provided effective symptomatic relief for severe oral lichen planus, but side-effects were common, and six patients stopped treatment because of them.