Low sex-hormone binding globulin levels in young women with diffuse hair loss


Dr J.A.Miller, Senior Registrar, Department of Dermatology, The Middlesex Hospital, London W1N 8AA.


We measured plasma sex-hormone binding globulin (SHBG) and testosterone levels in a pilot study of eight women aged 21–41 years who complained of diffuse hair loss; and subsequently in a larger group of fifteen patients of a similar age range. There was a significant reduction in SHBG levels in both groups of patients when compared to controls, but testosterone values were normal.