Treatment of rosacea with 1% metronidazole cream. A double-blind study
Article first published online: 29 JUL 2006
British Journal of Dermatology
Volume 108, Issue 3, pages 327–332, March 1983
How to Cite
NIELSEN, P.GAMBORG. (1983), Treatment of rosacea with 1% metronidazole cream. A double-blind study. British Journal of Dermatology, 108: 327–332. doi: 10.1111/j.1365-2133.1983.tb03972.x
- Issue published online: 29 JUL 2006
- Article first published online: 29 JUL 2006
Eighty-one patients with rosacea were treated with either i % metronidazole cream or the cream base as a placebo for two months. The trial was performed double-blind, and the patients were assessed once each month. The variates studied were: (i) overall clinical assessment, (2) lesion counts, (3) degree of erythema, (4) independent photographic evaluation, and (5) patient's opinion.
Four patients dropped out of the trial (one treated with metronidazole, three with placebo). In all the variates, 1% metronidazole cream proved to be significantly more effective than placebo.