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Dermal elastosis in hairless mice after UV-B and UV-A applied simultaneously, separately or sequentially
Article first published online: 29 JUL 2006
DOI: 10.1111/j.1365-2133.1984.tb04675.x
1365-2133/asset/cover.gif?v=1&s=413074e1e506a67a21dcc4e2de9ff9b6ce256d16 "British Journal of Dermatology")
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How to Cite
POULSEN, J.T., STABERG, B., WULF, H.C. and BRODTHAGEN, H. (1984), Dermal elastosis in hairless mice after UV-B and UV-A applied simultaneously, separately or sequentially. British Journal of Dermatology, 110: 531–538. doi: 10.1111/j.1365-2133.1984.tb04675.x
Publication History
- Issue published online: 29 JUL 2006
- Article first published online: 29 JUL 2006
- Accepted for publication 19 October 1983
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SUMMARY
The elastosis-inducing capacity of UV-A and UV-B was studied in the skin of hairless mice. After irradiation with UV-B and UV-A applied either simultaneously, separately or sequentially, the degree of elastosis in the dermis was microscopically evaluated. This semi-quantitative method showed no significant elastosis in the UV-A irradiated mice, and moderate elastosis in the UV-B irradiated mice. Heavy elastosis was observed when the mice were exposed sequentially to UV-B and a large dose of UV-A, but if a moderate dose of UV-A was given simultaneously with UV-B, the degree of elastosis was slightly reduced compared with the elastosis induced by UV-B alone.