SEARCH

SEARCH BY CITATION

SUMMARY

Sebum excretion and acne grades were measured in 20 pairs each of identical and non-identical like-sex twins. The identical twins had virtually identical rates of sebum excretion (P > 0·05), but they had a significantly different degree of acne severity (P < 0·01). The non-identical twins had significantly different sebum excretion rates (P > 0·01) and acne grades (P < 0·01). These findings suggest that sebum excretion is under genetic control and the development of clinical lesions is modified by environmental factors.