Conflicts of interest: None declared.
Sclerosing panniculitis is associated with pulmonary hypertension in systemic sclerosis
Article first published online: 19 AUG 2005
British Journal of Dermatology
Volume 153, Issue 3, pages 579–583, September 2005
How to Cite
Jinnin, M., Ihn, H., Asano, Y., Yamane, K., Yazawa, N. and Tamaki, K. (2005), Sclerosing panniculitis is associated with pulmonary hypertension in systemic sclerosis. British Journal of Dermatology, 153: 579–583. doi: 10.1111/j.1365-2133.2005.06680.x
- Issue published online: 19 AUG 2005
- Article first published online: 19 AUG 2005
- Accepted for publication 7 February 2005
- pulmonary embolism;
- pulmonary hypertension;
- sclerosing panniculitis;
- systemic sclerosis
Background There have been no reports of patients with sclerosing panniculitis and systemic sclerosis (SSc).
Objectives To evaluate the incidence of sclerosing panniculitis in patients with SSc, and to investigate the clinical features of such cases.
Methods In total, 128 patients with SSc treated at our clinic were investigated retrospectively.
Results SSc patients with sclerosing panniculitis had pulmonary hypertension (PH), especially isolated PH, at a significantly higher incidence than those without. Among the SSc patients with PH, those with sclerosing panniculitis had pulmonary infarctions at a higher incidence than those without.
Conclusions Our results suggest that thrombosis caused by venous hypertension of the leg may be the main cause of PH in patients with SSc and sclerosing panniculitis. Sclerosing panniculitis may be a useful marker of PH in patients with SSc.