Epidemiology and aetiology of basal cell carcinoma


  • Conflicts of interest ES acts as a consultant to Meda Pharma. All remaining authors declare no conflict of interest.

Joachim Roewert-Huber.
E-mail: joachim.roewert@charite.de


Basal cell carcinoma (BCC) is a malignant epithelial neoplasm of the skin preferentially affecting male caucasians and is rarely observed in patients with more intense skin pigmentation. A characteristic feature of BCCs are their extremely low risk to metastasize. Epidemiological data indicate that the overall incidence is increasing worldwide significantly by about 3–10% per annum.1–3 Based on the increasing incidence of this usually not life-threatening tumour BCC appears to develop into a growing public health problem. This review elucidates the risk factors for the development and for the progression of BCC leading to an improved understanding of this tumour.