Conflicts of interest None declared.
Infantile-onset cutaneous T-cell lymphoma
Article first published online: 20 AUG 2008
© 2008 The Authors. Journal Compilation © 2008 British Association of Dermatologists
British Journal of Dermatology
Volume 159, Issue 6, pages 1338–1341, December 2008
How to Cite
Tsianakas, A., Kienast, A.K. and Hoeger, P.H. (2008), Infantile-onset cutaneous T-cell lymphoma. British Journal of Dermatology, 159: 1338–1341. doi: 10.1111/j.1365-2133.2008.08794.x
Current affiliation of A.T.: Department of Dermatology, University of Münster, Münster, Germany
- Issue published online: 19 NOV 2008
- Article first published online: 20 AUG 2008
- Accepted for publication 24 January 2008
- cutaneous T-cell lymphoma;
- mycosis fungoides
Background Mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma (CTCL), is mainly a disease of the elderly.
Objectives To review paediatric CTCL cases reported in the literature, with a focus on the time between onset of symptoms and establishment of a correct diagnosis.
Methods A review of the literature was carried out and a case reported.
Results A total of 254 cases of CTCL have been reported in children aged < 16 years, 13 cases (< 1% of all reported cases) in children below the age of 2 years, and only seven cases (including ours) during the first year of life. CTCL was most prevalent in children aged 10–12 years. The delay between age of onset and establishment of diagnosis was largest in the youngest age group (0–3 years), and declined steadily thereafter, thus reflecting the increasing likelihood that CTCL is considered in the differential diagnosis of skin disorders with increasing age of the patient.
Conclusions The diagnosis of CTCL is frequently delayed in young children. It needs to be considered in chronic ‘eczematous’ skin lesions irrespective of the patient’s age, and including infants.