Funding sources None.
A microbial aetiology of acne: what is the evidence?
Article first published online: 28 AUG 2011
© 2011 The Authors. BJD © 2011 British Association of Dermatologists
British Journal of Dermatology
Volume 165, Issue 3, pages 474–485, September 2011
How to Cite
Shaheen, B. and Gonzalez, M. (2011), A microbial aetiology of acne: what is the evidence?. British Journal of Dermatology, 165: 474–485. doi: 10.1111/j.1365-2133.2011.10375.x
Conflicts of interest None declared.
- Issue published online: 28 AUG 2011
- Article first published online: 28 AUG 2011
- Accepted manuscript online: 18 APR 2011 03:19AM EST
- Accepted for publication 5 April 2011
A microbial aetiology of acne has been suggested since the beginning of the last century. There is considerable evidence, circumstantial at best, which suggests that micro-organisms, particularly Propionibacterium acnes, are important in the pathogenesis of acne vulgaris. However, it is still unclear whether P. acnes is actually a causal agent in the development of noninflamed or inflamed acne lesions. Based on a review of the microbiological data on normal and acne-affected skin, we propose that P. acnes neither initiates comedogenesis nor has a role in the initiation of inflammation in inflamed acne lesions.