Funding sources: we gratefully acknowledge Epiderm (formerly the Australasian Dermatology Research and Education Foundation) for funding this study. The Melbourne Collaborative Cohort Study is supported by the Australian National Health and Medical Research Council (NHMRC) (grants 209057, 251533, 396414, 504711). Cohort recruitment and follow-up is funded by The Cancer Council Victoria. J.A.E. is supported by a NHMRC capacity building grant in population health.
Association analysis of oestrogen receptor beta gene (ESR2) polymorphisms with female pattern hair loss
Version of Record online: 5 MAR 2012
© 2012 The Authors. BJD © 2012 British Association of Dermatologists
British Journal of Dermatology
Volume 166, Issue 5, pages 1131–1134, May 2012
How to Cite
Yip, L., Zaloumis, S., Irwin, D., Severi, G., Hopper, J., Giles, G., Harrap, S., Sinclair, R. and Ellis, J. (2012), Association analysis of oestrogen receptor beta gene (ESR2) polymorphisms with female pattern hair loss. British Journal of Dermatology, 166: 1131–1134. doi: 10.1111/j.1365-2133.2011.10702.x
Conflicts of interest: none declared.
- Issue online: 23 APR 2012
- Version of Record online: 5 MAR 2012
- Accepted manuscript online: 20 OCT 2011 11:12AM EST
Figure S1. GENEVAR database evidence of differential expression of ESR2 in fibroblast cells in the presence of the CC genotype of rs10137185.
Table S1. List of single nucleotide polymorphisms (SNPs) tagged by the selected 32 tag SNPs and their location in the ESR2 gene region.
Table S2 (a) Sub-analysis of genotypes comprising alleles of the tag single nucleotide polymorphism (SNP) rs10137185 using a codominant genetic model in χ2 analysis; Fisher-exact test was used when genotype frequency was < 5. (b) Sub-analysis of genotypes comprising alleles of the tag single nucleotide polymorphism (SNP) rs17101774 using χ2 analysis; Fisher-exact test was used when genotype frequency was < 5. There were no minor allele homozygotes for this tag SNP.
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