Funding sources This work was partly supported by a National Health and Medical Research Council Career Development Fellowship to P.D. Baade (#1005334). The NH&MRC did not have any role in the preparation or decision to submit this manuscript.
EPIDEMIOLOGY AND HEALTH SERVICES RESEARCH
Changes in the site distribution of common melanoma subtypes in Queensland, Australia over time: implications for public health campaigns
Article first published online: 13 SEP 2012
© 2012 The Authors. BJD © 2012 British Association of Dermatologists
British Journal of Dermatology
Volume 168, Issue 1, pages 136–144, January 2013
How to Cite
Youl, P.H., Youlden, D.R. and Baade, P.D. (2013), Changes in the site distribution of common melanoma subtypes in Queensland, Australia over time: implications for public health campaigns. British Journal of Dermatology, 168: 136–144. doi: 10.1111/j.1365-2133.2012.11064.x
Conflicts of interest None declared.
- Issue published online: 21 DEC 2012
- Article first published online: 13 SEP 2012
- Accepted manuscript online: 21 MAY 2012 08:24AM EST
- Accepted for publication 14 May 2012
Background An examination of melanoma incidence according to anatomical region may be one method of monitoring the impact of public health initiatives.
Objectives To examine melanoma incidence trends by body site, sex and age at diagnosis or body site and morphology in a population at high risk.
Materials and methods Population-based data on invasive melanoma cases (n = 51 473) diagnosed between 1982 and 2008 were extracted from the Queensland Cancer Registry. Age-standardized incidence rates were calculated using the direct method (2000 world standard population) and joinpoint regression models were used to fit trend lines.
Results Significantly decreasing trends for melanomas on the trunk and upper limbs/shoulders were observed during recent years for both sexes under the age of 40 years and among males aged 40–59 years. However, in the 60 and over age group, the incidence of melanoma is continuing to increase at all sites (apart from the trunk) for males and on the scalp/neck and upper limbs/shoulders for females. Rates of nodular melanoma are currently decreasing on the trunk and lower limbs. In contrast, superficial spreading melanoma is significantly increasing on the scalp/neck and lower limbs, along with substantial increases in lentigo maligna melanoma since the late 1990s at all sites apart from the lower limbs.
Conclusions In this large study we have observed significant decreases in rates of invasive melanoma in the younger age groups on less frequently exposed body sites. These results may provide some indirect evidence of the impact of long-running primary prevention campaigns.