Funding sources None.
DERMATOLOGICAL SURGERY AND LASERS
Mohs surgery for squamous cell carcinoma of the nail: report of 15 cases. Our experience and a long-term follow-up
Article first published online: 26 NOV 2012
© 2012 The Authors. BJD © 2012 British Association of Dermatologists
British Journal of Dermatology
Volume 167, Issue 6, pages 1310–1314, December 2012
How to Cite
Dika, E., Piraccini, B.M., Balestri, R., Vaccari, S., Misciali, C., Patrizi, A. and Fanti, P.A. (2012), Mohs surgery for squamous cell carcinoma of the nail: report of 15 cases. Our experience and a long-term follow-up. British Journal of Dermatology, 167: 1310–1314. doi: 10.1111/j.1365-2133.2012.11129.x
Conflicts of interest None declared.
- Issue published online: 26 NOV 2012
- Article first published online: 26 NOV 2012
- Accepted manuscript online: 4 JUL 2012 02:20PM EST
- Accepted for publication 27 June 2012
Background Subungual squamous cell carcinoma (SSCC) is the most common malignancy of the nail unit. Mohs micrographic surgery (MMS) is a microscopically controlled surgical technique that has a high cure rate for skin cancers despite allowing narrow surgical margins.
Objective To evaluate the long-term effectiveness of MMS in the treatment of SSCC, and in particular its ability to reduce the number of digital amputations.
Methods Fifteen patients diagnosed with SSCC were treated with MMS as the first-line surgical approach, and were followed up for between 2 and 5 years.
Results SSCC was completely excised in 13 patients, while two patients required amputation of the distal phalanx. For tumours with predominantly exophytic growth, clinical and radiological findings were found not to be reliable indicators of bone invasion. No recurrences were detected on follow-up.
Conclusion Our results show that MMS provides a high cure rate for SSCC and reduces the number of amputations needed. MMS should become the first-line surgical approach for SSCC.