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Keywords:

  • leukaemic mantle cell lymphoma;
  • hyperdiploid cells;
  • t(ll;14)(q!3;q32);
  • BCL1/CCND11

The present study describes five patients with leukaemic non-Hodgkin's lymphoma (NHL) detected on the basis of particular morphology and cytogenetic findings. With respect to histological, immunological and cytogenetic features these NHL are closely related to mantle cell Iymphoma/intermediate differentiated lymphocytic lymphoma. However, the presence of unusual large cells associated with the t(ll;14)(ql3;q32) translocation and numerical chromosome changes, in the near triploid or near tetraploid range, could delineate a particular subtype of mantle cell lymphoma.