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A 70-year-old woman with chemotherapy-resistant acute myelomonocytic leukaemia complained of a sudden chest pain whilst neutropenic as a result of salvage therapy.

Computed tomography of the chest showed narrowing of the lumen of her descending aorta (top left). Despite antimicrobial treatment (biapenem, arbekacin and fluconazole), she died of multiple organ failure. Autopsy showed an Aspergillus thrombus, almost completely occluding the lumen of the aorta (right: macroscopic image; bottom left: Grocott stain).